With the growing number of novel therapeutic approaches for liver diseases, significant
research efforts have been devoted to the development of liquid biopsy tools for precision …

This review intends to uncover how information from large-scale genetic profiling (whole
genome sequencing, and whole exome sequencing) of nonalcoholic fatty liver disease …

Activation of hepatic stellate cells (HSCs) is a central driver of liver fibrosis. Previous
investigations have identified various altered epigenetic landscapes during the cellular …

Simple Summary Hepatocellular carcinoma (HCC) is one of the mostly lethal cancers, with a
prognosis which is still very poor. Novel reliable biomarkers, useful in early diagnosis and …

Alcohol-related liver disease (ARLD) is a primary cause of chronic liver disease in the
United States. Despite advances in the diagnosis and management of ARLD, it remains a …

Peroxisome proliferator-activated receptor-γ (PPARγ) belongs to the superfamily of nuclear
receptors that control the transcription of multiple genes. Although it is found in many cells …

Circulating cell-free DNA (cfDNA) and RNA (cfRNA) hold enormous potential as a new class
of biomarkers for the development of noninvasive liquid biopsies in many diseases and …

Methods: A total of 139 consecutive biopsy-proven nonalcoholic fatty liver disease patients
were enrolled in the study. We calculated the noninvasive scores and performed liver …

Objective Clinical relevance of global DNA methylation and one‐carbon metabolite levels
with histological severity remains uncertain in patients with nonalcoholic fatty liver disease …

Nonalcoholic fatty liver disease (NAFLD) is becoming the most frequent chronic liver
disease worldwide. Metabolic (dysfunction) associated fatty liver disease (MAFLD) is …