The rational choice and design of biomaterials for biomedical applications is crucial for
successful in vitro and in vivo strategies, ultimately dictating their performance and potential …

The adult heart is a vital and highly specialized organ of the human body, with limited
capability of self-repair and regeneration in case of injury or disease. Engineering …

This study evaluated the safety and feasibility of transendocardial injections of VentriGel, a
cardiac extracellular matrix hydrogel, in early and late post–myocardial infarction (MI) …

Bone marrow mesenchymal stem cell (MSC)-derived small extracellular vesicles (sEVs)
have been widely used for treating myocardial infarction (MI). However, low retention and …

Cardiovascular diseases (CVD) constitute a major fraction of the current major global
diseases and lead to about 30% of the deaths, ie, 17.9 million deaths per year. CVD include …

Myocardial infarction (MI) has been considered as the leading cause of cardiovascular-
related deaths worldwide. Although traditional therapeutic agents including various …

Cardiovascular diseases, including myocardial infarction (MI), represent the main worldwide
cause of mortality and morbidity. In this scenario, to contrast the irreversible damages …

Mitochondrial dysfunction of cardiomyocytes (CMs) has been identified as a significant
pathogenesis of early myocardial infarction (MI). However, only a few agents or strategies …

Cardiovascular diseases are the primary cause of death worldwide. Despite significant
advances in pharmacological treatments and surgical interventions to restore heart function …

Aims AUGMENT‐HF was an international, multicentre, prospective, open‐label,
randomized, controlled evaluation testing the hypothesis that Algisyl (injectable calcium …