Abstract Classical macrolides containing 14-or 15-membered aglycone lactone rings are
basic and widely used antibacterial agents in clinical therapy. Macrolides exert antibacterial …

This review provides an overview of the most important novel treatment strategies against
Streptococcus pneumoniae infections published over the past 10 years. The pneumococcus …

Macrozones are novel conjugates of azithromycin and thiosemicarbazones, which exhibit
very good in vitro antibacterial activities against susceptible and some resistant bacterial …

HSV disease is distributed worldwide. Anti-herpesvirus drugs are a problem in clinical
settings, particularly in immunocompromised individuals undergoing herpes simplex virus …

Staphylococcus aureus (S. aureus), recognized as one of the deadliest pathogens
responsible for nosocomial and community acquired infections, is highly contagious and …

Heterocyclic compounds have been at the hierarchy position in academia, and industrial
arena, particularly the compounds containing triazole-core are found to be potent with a …

The sustained rise of antimicrobial resistance (AMR) causes a strong need to develop new
antibacterial agents. One of the methods for addressing the problem of antibiotic resistance …

LC-SPE/cryo NMR and MS methodologies have been developed and employed for a rapid
structure determination of 4 ″-tetrahydrofurfuryl macrozone reaction mixture components …

Macrolide antibiotics have a durable history of successful development, effectiveness, and
safety since their discovery in 1952. Macrolides range from the prototypical erythromycin …

Synthesis of mono- and difluorobenzyl chlorides by chlorination of mono- and
difluorotoluenes with CCl4 and t-BuOCl induced by iron-containing catalysts …