Ambient particulate matter exposure induces ferroptosis in hippocampal cells through the GSK3B/Nrf2/GPX4 pathway
J Gui, L Wang, J Liu, H Luo, D Huang, X Yang… - Free Radical Biology …, 2024 - Elsevier
Epidemiological studies have established a robust correlation between exposure to ambient
particulate matter (PM) and various neurological disorders, with dysregulation of intracellular …
particulate matter (PM) and various neurological disorders, with dysregulation of intracellular …
Ameliorating and Therapeutic Impact of Curcumin Nanoparticles Against Aluminum Oxide Nanoparticles Induced Kidney Toxicity, DNA Damage, Oxidative Stress …
E Tousson, IET El‐Sayed… - Environmental …, 2024 - Wiley Online Library
Aluminum oxide nanoparticles (Al2O3 NPs) are among the most extensively utilized
nanoparticles in nanotechnology and that have negative impacts on the environment …
nanoparticles in nanotechnology and that have negative impacts on the environment …
Donepezil protects against cyclophosphamide-induced premature ovarian failure in mice: A focus on proinflammatory cytokines and NLRP3/TLR-4/NF-κB interplay
A Zidan, M Elnady, BN Khalifa - Toxicology and Applied Pharmacology, 2024 - Elsevier
Background and aim Cyclophosphamide (CP) chemotherapy is a significant iatrogenic
component of premature ovarian failure (POF). The aim of this work was to evaluate the …
component of premature ovarian failure (POF). The aim of this work was to evaluate the …
Salidroside alleviates cholestasis-induced liver fibrosis by inhibiting hepatic stellate cells via activation of the PI3K/AKT/GSK-3β signaling pathway and regulating …
X Wang, S Cao, Y Huang, L Li, D Xu… - Frontiers in Pharmacology, 2024 - frontiersin.org
Salidroside (SAL), a phenylpropanoid bioactive compound, has various pharmacological
properties, including antioxidant, anti-inflammatory, and hepatoprotective effects. However …
properties, including antioxidant, anti-inflammatory, and hepatoprotective effects. However …
Study on multi-target effects of the novel HDAC6 inhibitor W5 on Aβ/Cu2+-induced Alzheimer's disease model of rats
R Liu, L Guo, Y Zhao, D Wu, J Yu, P Liu - Brain Research, 2024 - Elsevier
Abstract Histone deacetylase 6 (HDAC6) is a key therapeutic target in neurodegenerative
diseases such as Alzheimer's disease (AD), which has been demonstrated to play an …
diseases such as Alzheimer's disease (AD), which has been demonstrated to play an …
Anti-oxidant activity of coenzyme Q10 against AlCl3/D-galactose in albino rat induced cognitive dysfunctions: Behavioral, biochemical, and BACE-1/GSK-3β …
The relationship between amyloid beta (Aβ) and oxidative stress (OS), both prominent
factors in Alzheimer's disease-related neural degeneration, is deeply interconnected. The …
factors in Alzheimer's disease-related neural degeneration, is deeply interconnected. The …
Auranofin-loaded PLGA nanoparticles alleviate cognitive deficit induced by streptozotocin in rats model: modulation of oxidative stress, neuroinflammatory markers …
SK Kushawaha, MS Ashawat, A Baldi - Naunyn-Schmiedeberg's Archives …, 2024 - Springer
Alzheimer's disease remains an unsolved neurological puzzle with no cure. Current
therapies offer only symptomatic relief, hindered by limited uptake through the blood–brain …
therapies offer only symptomatic relief, hindered by limited uptake through the blood–brain …