Cognitive impairments reported across psychiatric conditions (ie, major depressive disorder,
bipolar disorder, schizophrenia, and posttraumatic stress disorder) strongly impair the …

Mental disorders represent common brain diseases characterized by substantial
impairments of social and cognitive functions. The neurobiological causes and mechanisms …

Dopamine is one of the neurotransmitters whose transmission is altered in a number of
neural pathways in the brain of schizophrenic patients. Current evidence indicates that these …

The implication of neuroinflammation in schizophrenia, sustained by recent genetic
evidence, represents one of the most exciting topics in schizophrenia research. Drugs which …

It has been hypothesized that oxidative imbalance and alterations in nitrergic signaling play
a role in the neurobiology of schizophrenia. Preliminary evidence suggests that adjunctive …

Synaptic plasticity alters the strength of information flow between presynaptic and
postsynaptic neurons and thus modifies the likelihood that action potentials in a presynaptic …

Abstract Neuronal growth regulator 1 (NEGR1) belongs to the immunoglobulin (IgLON)
superfamily of cell adhesion molecules involved in cortical layering. Recent functional and …

Many mammals are born in a very immature state and develop their rich repertoire of
behavioral and cognitive functions postnatally. This development goes in parallel with …

The ventral striatum is a reward center implicated in the pathophysiology of depression. It
contains islands of Calleja, clusters of dopamine D3 receptor-expressing granule cells …

Most neurons are generated during development and are not replaced during adulthood,
even if they are lost to injury or disease. However, it is firmly established that new neurons …