Polymer nanomaterials for use as adjuvant surgical tools

M Erdi, A Sandler, P Kofinas - Wiley Interdisciplinary Reviews …, 2023 - Wiley Online Library
Materials employed in the treatment of conditions encountered in surgical and clinical
practice frequently face barriers in translation to application. Shortcomings can be …

An injectable, robust double network adhesive hydrogel for efficient, real-time hemostatic sealing

W Zhang, S Song, J Huang, Z Zhang - Chemical Engineering Journal, 2023 - Elsevier
Despite significant progress in bioadhesive hydrogels, achieving injectable adhesives with
robust mechanical strength, strong wet-tissue adhesion and anti-postoperative tissue …

Controlled release of a therapeutic peptide in sprayable surgical sealant for prevention of postoperative abdominal adhesions

M Erdi, MS Saruwatari, S Rozyyev, C Acha… - … Applied Materials & …, 2023 - ACS Publications
Formation of asymmetric, rigid scar tissue known as surgical adhesions is caused by
traumatic disruption of mesothelial-lined surfaces in surgery. A widely adopted prophylactic …

Nonswellable Hydrogel Patch with Tissue-Mimetic Mechanical Characteristics Remodeling In Vivo Microenvironment for Effective Adhesion Prevention

X Liu, X Qiu, L Nie, B Zhou, P Bu, Y Li, X Xue, B Tang… - ACS …, 2024 - ACS Publications
Postoperative adhesion is a common complication after abdominal surgery, but current
clinical products have unsatisfactory therapeutic effects. Here, we present a hydrogel patch …

Real-time fluorescence-guided adhesiolysis with indocyanine green in intra-abdominal surgery (with video)

Q Chen, Y Cai, K Cheng, Z Chen, J Li, S Wu… - Scientific Reports, 2024 - nature.com
Intra-abdominal adhesions have consistently posed a challenge for surgeons during
procedures. This study aims to investigate the feasibility of utilizing indocyanine green (ICG) …

Synthesis of shape-programmable elastomer for a bioresorbable, wireless nerve stimulator

JH Lim, WB Han, TM Jang, GJ Ko, JW Shin… - Biosensors and …, 2024 - Elsevier
Materials that have the ability to manipulate shapes in response to stimuli such as heat, light,
humidity and magnetism offer a means for versatile, sophisticated functions in soft robotics …

ROS-responsive sprayable hydrogel as ROS scavenger and GATA6+ macrophages trap for the prevention of postoperative abdominal adhesions

Y Huang, X Dai, Y Gong, L Ren, Y Luo, Y Sun… - Journal of Controlled …, 2024 - Elsevier
Postoperative abdominal adhesions are a common clinical problem after surgery and can
cause many serious complications. Current most commonly used antiadhesion products are …

Automatic in situ short-distance deposition of PLGA/PLLA composite nanofibrous membranes for personalized wound dressings

Y Liu, B Xia, R Zhao, M Qin, X Weng, Z Zeng, K Deng… - Nanoscale, 2024 - pubs.rsc.org
Improving the mechanical properties of wound dressings and achieving personalized
automatic real-time in situ deposition are important for accelerating wound management and …

CuSO4/H2O2 induced polydopamine/polysulfobetaine methacrylate co-deposition on poly (amino acid) membranes for improved anti-protein adsorption and …

X Chen, D Yan, H Deng, H Yang, S Peng… - Biomedical …, 2024 - iopscience.iop.org
Stopping postoperative soft tissue adhesions is one of the most challenging clinical
problems that needs to be addressed urgently to avoid secondary injury and pain to …

From Adhesion to Detachment: Strategies to Design Tissue‐Adhesive Hydrogels

MH Ho, Q van Hilst, X Cui… - Advanced …, 2024 - Wiley Online Library
The use of tissue adhesives dates to 1940s when surgical glues were introduced for wound
closure applications. However, current clinically used tissue adhesives (fibrin and …