Learning Objectives After completing this course, the reader will be able to: List the different
major subtypes of glioma and identify the appropriate treatment strategies for patients with …

Gliomatosis cerebri (GC) is a rare disease, defined as a diffuse neoplastic glial cell
infiltration of the brain. Diagnosis and management of GC are difficult. This study analyzed …

Gliomatosis cerebri is a rare diffusely infiltrating primary neoplastic glial process of the brain.
Our objective is to review clinical presentation, management, and outcome in a large single …

Gliomatosis cerebri (GC) is a rare, extensively infiltrating glioma involving multiple
contiguous lobes of the brain. This lethal disease affects all age groups, and the majority of …

Objective: The NOA‐05 multicenter trial was performed to analyze the efficacy of primary
chemotherapy with procarbazine and lomustine (PC) in patients with gliomatosis cerebri …

Medical treatments for glioblastoma face several challenges. Lipophilic alkylators remain the
mainstay of treatment, emphasising the primacy of good blood–brain barrier penetration …

Background: Up-front temozolomide (TMZ) has been recently proposed as a treatment for
gliomatosis cerebri (GC), but no predictive or prognostic markers have been identified so far …

Gliomatosis cerebri (GC) constitutes a heterogenous group of conditions involving diffuse
neoplastic glial cell infiltration of the brain. Management is difficult and an obvious challenge …

Gliomatosis cerebri (GC) is a universally fatal extensive and diffuse infiltration of brain
parenchyma by a glial tumor. Many aspects of this phenomenon remain unknown. The First …

Opinion statement Gliomatosis cerebri (GC) is an intriguing disease for several reasons.
First, it is difficult to draw the border between GC and diffuse gliomas. In this regard, GC …