Importance Cerebral small vessel disease (cSVD) is a common cause of stroke (lacunar
stroke), is the most common cause of vascular cognitive impairment, and impairs mobility …

Cerebral small vessel disease (cSVD) causes lacunar stroke (25% of ischaemic strokes),
haemorrhage, dementia, physical frailty, or is 'covert', but has no specific treatment …

Abstract Alzheimer's disease (AD), the leading cause of dementia, is characterized by the
accumulation of amyloid plaques and neurofibrillary tangles in the brain. This condition …

Background and Objectives The severity of white matter hyperintensities (WMH) at
presentation with stroke is associated with poststroke dementia and dependency. However …

Background Small vessel disease causes a quarter of ischaemic strokes (lacunar subtype),
up to 45% of dementia either as vascular or mixed types, cognitive impairment and physical …

A new dawn of preventing dementia by preventing cerebrovascular diseases | The BMJ
Skip to main content Intended for healthcare professionals Access provided by Google …

Background: There is increasing interest in the concept of frailty in stroke, including both
physical frailty and imaging-evidence of brain frailty. We aimed to establish the prevalence …

Background Stroke commonly affects cognition and, by definition, much vascular dementia
follows stroke. However, there are fundamental limitations in our understanding of vascular …

The present study aimed to evaluate the preventive role of physical and cognitive training
separately or in combination on memory dysfunction, inflammatory factors and apoptotic …

Background and purpose Cognitive impairment is a common sequel of recent small
subcortical infarction (RSSI) and might be negatively affected by preexisting cerebral small …