[HTML][HTML] European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)

J Egea, I Fabregat, YM Frapart, P Ghezzi, A Görlach… - Redox biology, 2017 - Elsevier
Abstract The European Cooperation in Science and Technology (COST) provides an ideal
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …

Therapeutic angiogenesis for critical limb ischaemia

BH Annex - Nature Reviews Cardiology, 2013 - nature.com
Peripheral arterial disease (PAD) is caused by occlusive atherosclerosis in a vascular bed
other than the heart. The lower extremity is the most-common location for PAD. Critical limb …

Diabetic wound regeneration using peptide-modified hydrogels to target re-epithelialization

Y Xiao, LA Reis, N Feric, EJ Knee… - Proceedings of the …, 2016 - National Acad Sciences
There is a clinical need for new, more effective treatments for chronic wounds in diabetic
patients. Lack of epithelial cell migration is a hallmark of nonhealing wounds, and diabetes …

A systems biology perspective on sVEGFR1: its biological function, pathogenic role and therapeutic use

FTH Wu, MO Stefanini, FM Gabhann… - Journal of cellular …, 2010 - Wiley Online Library
Introduction‐Angiogenesis in physiology and pathology‐Angiogenesis in current medicine‐
VEGF ligand and receptor system: where does sVEGFR1 fit?‐Ligands: the human VEGF …

MicroRNA-615-5p regulates angiogenesis and tissue repair by targeting AKT/eNOS (protein kinase B/endothelial nitric oxide synthase) signaling in endothelial cells

B Icli, W Wu, D Ozdemir, H Li, HS Cheng… - … and Vascular Biology, 2019 - Am Heart Assoc
Objective—In response to tissue injury, the appropriate progression of events in
angiogenesis is controlled by a careful balance between pro and antiangiogenic factors. We …

Exercise training and peripheral arterial disease

TL Haas, PG Lloyd, HT Yang… - Comprehensive …, 2012 - Wiley Online Library
Peripheral arterial disease (PAD) is a common vascular disease that reduces blood flow
capacity to the legs of patients. PAD leads to exercise intolerance that can progress in …

Long noncoding RNA LEENE promotes angiogenesis and ischemic recovery in diabetes models

X Tang, Y Luo, D Yuan, R Calandrelli… - The Journal of …, 2023 - Am Soc Clin Investig
Impaired angiogenesis in diabetes is a key process contributing to ischemic diseases such
as peripheral arterial disease. Epigenetic mechanisms, including those mediated by long …

Systems biology of vascular endothelial growth factors

FM Gabhann, AS Popel - Microcirculation, 2008 - Taylor & Francis
Several cytokine families have roles in the development, maintenance, and remodeling of
the microcirculation. Of these, the vascular endothelial growth factor (VEGF) family is one of …

[PDF][PDF] Endothelial PGC-1α mediates vascular dysfunction in diabetes

N Sawada, A Jiang, F Takizawa, A Safdar, A Manika… - Cell metabolism, 2014 - cell.com
Endothelial dysfunction is a central hallmark of diabetes. The transcriptional coactivator PGC-
1α is a powerful regulator of metabolism, but its role in endothelial cells remains poorly …

Diabetes mellitus and ischemic diseases: molecular mechanisms of vascular repair dysfunction

KY Howangyin, JS Silvestre - Arteriosclerosis, thrombosis, and …, 2014 - Am Heart Assoc
In patients with diabetes mellitus, the ability of ischemic tissue to synchronize the molecular
and cellular events leading to restoration of tissue perfusion in response to the …