Triazoles and their derivatives: Chemistry, synthesis, and therapeutic applications

MM Matin, P Matin, MR Rahman… - Frontiers in molecular …, 2022 - frontiersin.org
Among the nitrogen-containing heterocyclic compounds, triazoles emerge with superior
pharmacological applications. Structurally, there are two types of five-membered triazoles: 1 …

An updated review on diverse range of biological activities of 1, 2, 4-triazole derivatives: Insight into structure activity relationship

O Gupta, T Pradhan, G Chawla - Journal of Molecular Structure, 2023 - Elsevier
Abstract Since its discovery 1, 2, 4-triazole ring has emerged as a prominent heterocyclic
scaffold in medicinal chemistry. It possesses a wide spectrum of biological activities such as …

Visible-light-induced tandem radical addition–cyclization of 2-aryl phenyl isocyanides catalysed by recyclable covalent organic frameworks

S Liu, W Pan, S Wu, X Bu, S Xin, J Yu, H Xu… - Green Chemistry, 2019 - pubs.rsc.org
A visible-light-induced tandem radical addition–cyclization sequence via 2-aryl phenyl
isocyanides as the starting material and two-dimensional covalent organic frameworks (2D …

Coordination chemistry and metal-involving reactions of amidoximes: Relevance to the chemistry of oximes and oxime ligands

DS Bolotin, NA Bokach, VY Kukushkin - Coordination Chemistry Reviews, 2016 - Elsevier
Although the versatile chemistry of conventional oximes has been extensively reviewed over
the years in both the organic chemistry literature and the coordination chemistry literature …

Triazole-modified peptidomimetics: an opportunity for drug discovery and development

A Staśkiewicz, P Ledwoń, P Rovero, AM Papini… - Frontiers in …, 2021 - frontiersin.org
Peptidomimetics play a fundamental role in drug design due to their preferential properties
regarding natural peptides. In particular, compounds possessing nitrogen-containing …

A Synthesis of 1H-Indazoles via a Cu(OAc)2-Catalyzed N–N Bond Formation

C Chen, G Tang, F He, Z Wang, H Jing… - Organic letters, 2016 - ACS Publications
A facile synthesis of 1 H-indazoles featuring a Cu (OAc) 2-catalyzed N–N bond formation
using oxygen as the terminal oxidant is described. The reaction of readily available 2 …

Photoredox Decarboxylative C(sp3)–N Coupling of α-Diazoacetates with Alkyl N-Hydroxyphthalimide Esters for Diversified Synthesis of Functionalized N-Alkyl …

CM Chan, Q Xing, YC Chow, SF Hung, WY Yu - Organic letters, 2019 - ACS Publications
Herein we report a metal-free photocatalytic coupling reaction for the synthesis of structurally
and functionally diverse N-alkyl hydrazones from α-diazoacetates and N-alkyl …

tert-Butyl nitrite triggered radical cascade reaction for synthesizing isoxazoles by a one-pot multicomponent strategy

L Chen, Z Wang, H Liu, X Li, B Wang - Chemical Communications, 2022 - pubs.rsc.org
A metal-free radical cyclization/dehydrogenation cascade of alkenes with aldehydes has
been developed for the synthesis of 3, 5-disubstituted isoxazoles in a one-pot system. This …

Visible light-induced cyclization reactions for the synthesis of 1, 2, 4-triazolines and 1, 2, 4-triazoles

H Wang, Y Ren, K Wang, Y Man, Y Xiang… - Chemical …, 2017 - pubs.rsc.org
A novel method for concisely synthesizing 1, 2, 4-triazolines via [3+ 2] cyclization under
visible light is reported. These compounds can be easily converted into 1, 2, 4-triazoles …

Substituted 1, 2, 3-triazoles: a new class of nitrification inhibitors

BI Taggert, C Walker, D Chen, U Wille - Scientific Reports, 2021 - nature.com
Nitrogen (N) fertilisers amended with nitrification inhibitors can increase nitrogen use
efficiencies in agricultural systems but the effectiveness of existing commercial inhibitor …