Perineural invasion (PNI), the neoplastic invasion of nerves, is a common pathologic finding
in head and neck cancer that is associated with poor clinical outcomes. PNI is a histologic …

The natural history of adenoid cystic carcinoma (ACC) is relentless, defined by treatment
failure heralded by locoregional recurrence and distant metastatic disease. In this review …

Perineural spread (PNS) represents the tumor's ability to disseminate along nerves. The aim
of this article is to review the relevant literature about the PNS in head-and-neck tumors. The …

Abstract Purpose of Review: Bell's palsy is a common outpatient problem, and while the
diagnosis is usually straightforward, a number of diagnostic pitfalls can occur, and a lengthy …

Perineural invasion (PNI) in cutaneous squamous cell carcinoma (SCC) of the periocular
region is a prognostic marker of adverse tumour outcomes. PNI carries a well-established …

OBJECTIVE Multiple approaches have been designed to reach the medial middle fossa (for
lesions in Meckel's cave, in particular), but an anterior approach through the greater wing of …

Background Perineural tumor spread (PNTS) to the brachial plexus (BP) is a rare and
challenging condition. This study aimed to elucidate the clinical presentations, diagnostic …

Background This study aimed to examine patients with facial nerve (VII) perineural spread
(PNS) from cutaneous squamous cell carcinoma of the head and neck. Methods …

Background Immune checkpoint inhibitors have shown promising antitumour activity.
Application in head and neck cutaneous squamous cell carcinoma (cSCC) large nerve …

Objectives/Hypothesis To describe outcomes of advanced head and neck cutaneous
squamous cell carcinoma (cSCC) with clinical perineural invasion (cPNI) treated with …