Adolescence is a time of major plasticity of brain systems that regulate motivated behavior
and cognition, and is also the age of peak onset of nicotine use. Although there has been a …

Given the rise in teenage use of electronic nicotine delivery systems (“vaping”) in
congruence with the increasing numbers of drug-related emergencies, it is critical to expand …

Concurrent use of tobacco and alcohol or psychostimulants represents a major public health
concern, with use of one substance influencing consumption of the other. Co-abuse of these …

Introduction A method for delivering vaporized nicotine to animals has been developed
using e-cigarette devices. The present experiment was designed to measure the effects of e …

Smoking remains the leading cause of preventable death in the United States. Although
combustible cigarettes are largely being replaced by tobacco-free products, nicotine use …

Introduction Initiation of tobacco products typically occurs in adolescence. Adolescence is a
critical period in development where the maturation of brain neurocircuitry is vulnerable to …

Abstract Alcohol and Methamphetamine (Meth) are widely abused drugs that are frequently
co-abused, though this pattern of polysubstance abuse is rarely studied. Alcohol use during …

There is a strong association between tobacco smoking and the consumption of alcoholic
beverages. When compared to the effects of either drug on its own, the combined use may …

Corticostriatal signaling participates in sensitized responses to drugs of abuse, where short-
term increases in dopamine availability provoke persistent, yet reversible, changes in …

The illicit use of the psychostimulant methamphetamine (METH) is a major concern, with
overdose deaths increasing substantially since the mid-2010s. One challenge to treating …