Neuregulins in neurodegenerative diseases
G Ou, W Lin, W Zhao - Frontiers in aging neuroscience, 2021 - frontiersin.org
Neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD)
and amyotrophic lateral sclerosis (ALS), are typically characterized by progressive neuronal …
and amyotrophic lateral sclerosis (ALS), are typically characterized by progressive neuronal …
Recent developments in new therapeutic agents against Alzheimer and Parkinson diseases: in-silico approaches
P Cruz-Vicente, LA Passarinha, S Silvestre, E Gallardo - Molecules, 2021 - mdpi.com
Neurodegenerative diseases (ND), including Alzheimer's (AD) and Parkinson's Disease
(PD), are becoming increasingly more common and are recognized as a social problem in …
(PD), are becoming increasingly more common and are recognized as a social problem in …
In silico molecular docking analysis of karanjin against alzheimer's and parkinson's diseases as a potential natural lead molecule for new drug design, development …
Parkinson's disease (PD) and Alzheimer's disease (AD) are neurodegenerative disorders
that have emerged as among the serious health problems of the 21st century. The …
that have emerged as among the serious health problems of the 21st century. The …
In vitro and in silico analysis of Thymus serpyllum essential oil as bioactivity enhancer of antibacterial and antifungal agents
D Salaria, R Rolta, CN Patel, K Dev… - Journal of …, 2022 - Taylor & Francis
Wild thyme (Thymus serpyllum L.) of family Laminaceae is an unexplored perennial
medicinal shrub. Aerial part of this plant is traditionally used for the treatment of respiratory …
medicinal shrub. Aerial part of this plant is traditionally used for the treatment of respiratory …
Computational investigation of natural compounds as potential main protease (Mpro) inhibitors for SARS-CoV-2 virus
Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) is significantly impacting human lives …
respiratory syndrome coronavirus 2 (SARS-CoV-2) is significantly impacting human lives …
Identification of 1, 3, 4-oxadiazoles as tubulin-targeted anticancer agents: a combined field-based 3D-QSAR, pharmacophore model-based virtual screening …
Cancer is one of the most prominent causes of death worldwide and tubulin is a crucial
protein of cytoskeleton that maintains essential cellular functions including cell division as …
protein of cytoskeleton that maintains essential cellular functions including cell division as …
Identification of potential inhibitors of coronavirus hemagglutinin-esterase using molecular docking, molecular dynamics simulation and binding free energy …
The pandemic outbreak of the Corona viral infection has become a critical global health
issue. Biophysical and structural evidence shows that spike protein possesses a high …
issue. Biophysical and structural evidence shows that spike protein possesses a high …
Phytochemical Analysis, In Vitro Biological Activities, and Computer-Aided Analysis of Potentilla nepalensis Hook Compounds as Potential Melanoma Inhibitors …
S Sharma, V Kumar, M Yaseen, A S. Abouzied… - Molecules, 2023 - mdpi.com
Potentilla nepalensis Hook is a perennial Himalayan medicinal herb of the Rosaceae family.
The present study aimed to evaluate biological activities such as the antioxidant …
The present study aimed to evaluate biological activities such as the antioxidant …
Structural and Computational Analyses of the Unique Interactions of Opicapone in the Binding Pocket of Catechol O-Methyltransferase: A Crystallographic Study and …
K Takebe, M Suzuki, T Kuwada-Kusunose… - Journal of Chemical …, 2023 - ACS Publications
A third-generation inhibitor of catechol O-methyltransferase (COMT), opicapone (1), has the
3-nitrocatechol scaffold as do the second-generation inhibitors such as entacapone (2) and …
3-nitrocatechol scaffold as do the second-generation inhibitors such as entacapone (2) and …
Molecular docking studies of phytocompounds of Rheum emodi Wall with proteins responsible for antibiotic resistance in bacterial and fungal pathogens: in silico …
R Rolta, D Salaria, V Kumar, CN Patel… - Journal of …, 2022 - Taylor & Francis
Abstract Rheum emodi Wall.(Himalayan rhubarb) has many pharmacological activities such
as antioxidant, antimicrobial, antiviral, anticancer and wound healing. The present study was …
as antioxidant, antimicrobial, antiviral, anticancer and wound healing. The present study was …