Central neural regulation of brown adipose tissue thermogenesis and energy expenditure
Thermogenesis, the production of heat energy, is the specific, neurally regulated, metabolic
function of brown adipose tissue (BAT) and contributes to the maintenance of body …
function of brown adipose tissue (BAT) and contributes to the maintenance of body …
Converging roles of ion channels, calcium, metabolic stress, and activity pattern of Substantia nigra dopaminergic neurons in health and Parkinson's disease
J Duda, C Pötschke, B Liss - Journal of neurochemistry, 2016 - Wiley Online Library
Dopamine‐releasing neurons within the Substantia nigra (SN DA) are particularly
vulnerable to degeneration compared to other dopaminergic neurons. The age‐dependent …
vulnerable to degeneration compared to other dopaminergic neurons. The age‐dependent …
AgRP neurons control systemic insulin sensitivity via myostatin expression in brown adipose tissue
SM Steculorum, J Ruud, I Karakasilioti, H Backes… - Cell, 2016 - cell.com
Activation of Agouti-related peptide (AgRP) neurons potently promotes feeding, and
chronically altering their activity also affects peripheral glucose homeostasis. We …
chronically altering their activity also affects peripheral glucose homeostasis. We …
Myeloid-cell-derived VEGF maintains brain glucose uptake and limits cognitive impairment in obesity
High-fat diet (HFD) feeding induces rapid reprogramming of systemic metabolism. Here, we
demonstrate that HFD feeding of mice downregulates glucose transporter (GLUT)-1 …
demonstrate that HFD feeding of mice downregulates glucose transporter (GLUT)-1 …
[HTML][HTML] Central nervous system regulation of brown adipose tissue
SF Morrison, CJ Madden - Comprehensive Physiology, 2014 - ncbi.nlm.nih.gov
Thermogenesis, the production of heat energy, in brown adipose tissue is a significant
component of the homeostatic repertoire to maintain body temperature during the challenge …
component of the homeostatic repertoire to maintain body temperature during the challenge …
Brain glucose sensing in homeostatic and hedonic regulation
L Steinbusch, G Labouèbe, B Thorens - Trends in Endocrinology & …, 2015 - cell.com
Glucose homeostasis as well as homeostatic and hedonic control of feeding is regulated by
hormonal, neuronal, and nutrient-related cues. Glucose, besides its role as a source of …
hormonal, neuronal, and nutrient-related cues. Glucose, besides its role as a source of …
Metabolic dysfunction in obstructive sleep apnea: a critical examination of underlying mechanisms
OA Mesarwi, EV Sharma, JC Jun… - Sleep and biological …, 2015 - Springer
It has recently become clear that obstructive sleep apnea (OSA) is an independent risk factor
for the development of metabolic syndrome, a disorder of defective energy storage and use …
for the development of metabolic syndrome, a disorder of defective energy storage and use …
Central noradrenaline transporter availability in highly obese, non-depressed individuals
S Hesse, GA Becker, M Rullmann, A Bresch… - European journal of …, 2017 - Springer
Purpose The brain noradrenaline (NA) system plays an important role in the central nervous
control of energy balance and is thus implicated in the pathogenesis of obesity. The specific …
control of energy balance and is thus implicated in the pathogenesis of obesity. The specific …
Astrocytic GLUT1 reduction paradoxically improves central and peripheral glucose homeostasis
CG Ardanaz, A de la Cruz, PS Minhas… - Science …, 2024 - science.org
Astrocytes are considered an essential source of blood-borne glucose or its metabolites to
neurons. Nonetheless, the necessity of the main astrocyte glucose transporter, ie, GLUT1 …
neurons. Nonetheless, the necessity of the main astrocyte glucose transporter, ie, GLUT1 …
[HTML][HTML] Neuronal modulation of brown adipose activity through perturbation of white adipocyte lipogenesis
A Guilherme, DJ Pedersen, F Henriques… - Molecular …, 2018 - Elsevier
Objective Crosstalk between adipocytes and local neurons may be an important regulatory
mechanism to control energy homeostasis. We previously reported that perturbation of …
mechanism to control energy homeostasis. We previously reported that perturbation of …