Evolution of drug delivery systems for recurrent aphthous stomatitis

I Suharyani… - Drug design …, 2021 - Taylor & Francis
Recurrent aphthous stomatitis (RAS) is a disease marked by painful oral lesions on the
buccal and labial mucosa or tongue. Drug delivery systems (DDS) for RAS include topical …

Integrating hippocampal metabolomics and network pharmacology deciphers the antidepressant mechanisms of Xiaoyaosan

X Liu, F Wei, H Liu, S Zhao, G Du, X Qin - Journal of Ethnopharmacology, 2021 - Elsevier
Ethnopharmacological relevance Xiaoyaosan (XYS), a classic description, has a history of
thousands of years for treating depression through invigorating the liver and strengthening …

[HTML][HTML] Therapeutic efficacy of Pudilan Xiaoyan Oral Liquid (PDL) for COVID-19 in vitro and in vivo

W Deng, Y Xu, Q Kong, J Xue, P Yu, J Liu… - Signal transduction and …, 2020 - nature.com
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2), has rapidly swept through the worldwide, with more than 3 …

[HTML][HTML] Analysis of the molecular mechanism of Pudilan (PDL) treatment for COVID-19 by network pharmacology tools

Q Kong, Y Wu, Y Gu, Q Lv, F Qi, S Gong… - Biomedicine & …, 2020 - Elsevier
Background Pudilan (PDL), a four-herb prescription with the traditional function of heat-
clearing and detoxifying, has been clinically used as an anti-SARS-CoV-2 infectory agent in …

Comprehensive evaluation of lipopolysaccharide-induced changes in rats based on metabolomics

C Geng, Y Guo, C Wang, C Cui, W Han… - Journal of …, 2020 - Taylor & Francis
Purpose Substantial evidence indicates that lipopolysaccharide (LPS) exposure can lead to
systemic inflammatory response syndrome (SIRS) and multiple organ failure. Previous …

A novel membrane-based integrated process for baicalin recovery from TCM Pudilan wastewater

X Zhang, R Ying, X Chen, Q Li, J Xu, J Qiu… - Journal of Water …, 2023 - Elsevier
This study aimed to investigate the potential of membrane integration technology for the
recovery of baicalin from Pudilan (PDL) industry wastewater. The impact of different …

Integrated metabolome-microbiome analysis investigates the different regulations of Pudilan Xiaoyan oral liquid in young rats with acute pharyngitis compared to adult …

K Ding, E Sun, R Huang, W Heng, X Li, J Liu, J Zhao… - Phytomedicine, 2023 - Elsevier
Abstract Background Pudilan Xiaoyan Oral Liquid (PDL) is a famous traditional Chinese
prescription recorded in the Chinese Pharmacopeia, which is widely used to treat …

Metabolomics combined with network pharmacology uncovers effective targets of Tao-Hong-Si-Wu decoction for its protection from sepsis-associated acute lung injury

J He, L Wang, Y Wang, Z Li, F Chen, Z Liu - Journal of Analysis and …, 2023 - Springer
Sepsis-induced acute lung injury (ALI) is a leading cause of death among septic
complications. Tao-Hong-Si-Wu decoction (TSD), a classical recipe from traditional Chinese …

Pudilan Keyanning mouthwash inhibits dextran-dependent aggregation and biofilm organization of Streptococcus mutans

S Ren, Y Cheng, Y Deng, M Xia, Y Yang… - Journal of Applied …, 2023 - academic.oup.com
Aims This research aimed to investigate the inhibitory effects of Pudilan mouthwash (PDL)
on Streptococcus mutans (S. mutans) biofilms and identify its chemical components …

Xiao‐Chai‐Hu Decoction Ameliorates Poly (I: C)‐Induced Viral Pneumonia through Inhibiting Inflammatory Response and Modulating Serum Metabolism

F Chen, F Qu, Y Jia, C Wang, Y Yu… - Evidence‐Based …, 2022 - Wiley Online Library
Viral pneumonia is widespread, progresses rapidly, and has a high mortality rate.
Developing safe and effective therapies to treat viral pneumonia can minimize risks to public …