Nutrition and prevention of cognitive impairment

N Scarmeas, CA Anastasiou… - The Lancet Neurology, 2018 - thelancet.com
Nutrition is an important lifestyle factor that can modify the risk of future cognitive impairment
and dementia. Some, but not conclusive, evidence (mostly from observational studies and …

[HTML][HTML] The vitamin D receptor as a potential target for the treatment of age-related neurodegenerative diseases such as Alzheimer's and Parkinson's diseases: A …

W Lasoń, D Jantas, M Leśkiewicz, M Regulska… - Cells, 2023 - mdpi.com
The vitamin D receptor (VDR) belongs to the nuclear receptor superfamily of transcription
factors. The VDR is expressed in diverse brain regions and has been implicated in the …

[HTML][HTML] Vitamin D deficiency as a risk factor for dementia and Alzheimer's disease: An updated meta-analysis

B Chai, F Gao, R Wu, T Dong, C Gu, Q Lin, Y Zhang - BMC neurology, 2019 - Springer
Background We aimed to comprehensively explore the associations between serum 25
(OH) D deficiency and risk of dementia and Alzheimer's disease (AD). Methods We …

[HTML][HTML] Does the high prevalence of vitamin D deficiency in African Americans contribute to health disparities?

BN Ames, WB Grant, WC Willett - Nutrients, 2021 - mdpi.com
African Americans have higher incidence of, and mortality from, many health-related
problems than European Americans. They also have a 15 to 20-fold higher prevalence of …

[HTML][HTML] Comparing the evidence from observational studies and randomized controlled trials for nonskeletal health effects of vitamin D

WB Grant, BJ Boucher, F Al Anouti, S Pilz - Nutrients, 2022 - mdpi.com
Although observational studies of health outcomes generally suggest beneficial effects with,
or following, higher serum 25-hydroxyvitamin D [25 (OH) D] concentrations, randomized …

[HTML][HTML] A narrative review of the evidence for variations in serum 25-hydroxyvitamin D concentration thresholds for optimal health

WB Grant, F Al Anouti, BJ Boucher, E Dursun… - Nutrients, 2022 - mdpi.com
Vitamin D3 has many important health benefits. Unfortunately, these benefits are not widely
known among health care personnel and the general public. As a result, most of the world's …

[HTML][HTML] Vitamin D and multiple health outcomes: an umbrella review of observational studies, randomized controlled trials, and Mendelian randomization studies

D Liu, X Meng, Q Tian, W Cao, X Fan, L Wu, M Song… - Advances in …, 2022 - Elsevier
Observational studies, randomized controlled trials (RCTs), and Mendelian randomization
(MR) studies have yielded inconsistent results on the associations of vitamin D …

[HTML][HTML] Vitamin D and brain health: an observational and Mendelian randomization study

SS Navale, A Mulugeta, A Zhou, DJ Llewellyn… - The American journal of …, 2022 - Elsevier
Background Higher vitamin D status has been suggested to have beneficial effects on the
brain. Objectives To investigate the association between 25-hydroxyvitamin D [25 (OH) D] …

[HTML][HTML] Vitamin D in neurological diseases

D Plantone, G Primiano, C Manco, S Locci… - International journal of …, 2022 - mdpi.com
Vitamin D may have multiple effects on the nervous system and its deficiency can represent
a possible risk factor for the development of many neurological diseases. Recent studies are …

Dose-response meta-analysis on tooth loss with the risk of cognitive impairment and dementia

X Qi, Z Zhu, BL Plassman, B Wu - Journal of the American Medical …, 2021 - Elsevier
Objectives To quantify the dose-response associations between tooth loss and risk of
cognitive impairment and dementia. Design Longitudinal studies that examined the …