The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …

Within the field of gene therapy, there is a considerable need for the development of non-
viral vectors that are able to compete with the efficiency obtained by viral vectors, while …

Operations with nucleic acids are among the main means of studying the mechanisms of
gene function and developing novel methods of molecular medicine and gene therapy …

The well-known Debus–Radziszewski reaction is over one century old. However, this
reaction has only been considered very recently as a new tool to design original imidazole …

Dicarboxylic acids have a wide range of applications in the polymer industry to construct
valuable materials. Photocatalysis has recently emerged as an efficient and sustainable …

Chain-transfer ring-opening metathesis polymerization (CT-ROMP) previously provided a
route to carboxytelechelic polyethylene (PE) of controlled molecular weight; however, the …

Two novel photochromic spirooxazines, SO 1 and SO 3, were successfully prepared and
characterized by Fourier transform infrared spectroscopy (FTIR), 1H‐NMR, and mass …

Safe and effective DNA delivery systems are required to enable or enhance clinical
strategies and research involving gene therapy and DNA vaccinations. To address this …

We present the facile synthesis of a clickable polymer library with systematic variations in
length, binary composition, pKa, and hydrophobicity (clog P) to optimize intracellular pDNA …

Polymer-based gene delivery relies on the binding, protection, and final release of nucleic
acid cargo using polycations. Engineering polymeric vectors, by exploring novel topologies …