Challenges and advances in clinical applications of mesenchymal stromal cells
T Zhou, Z Yuan, J Weng, D Pei, X Du, C He… - Journal of hematology & …, 2021 - Springer
Mesenchymal stromal cells (MSCs), also known as mesenchymal stem cells, have been
intensely investigated for clinical applications within the last decades. However, the majority …
intensely investigated for clinical applications within the last decades. However, the majority …
Shattering barriers toward clinically meaningful MSC therapies
More than 1050 clinical trials are registered at FDA. gov that explore multipotent
mesenchymal stromal cells (MSCs) for nearly every clinical application imaginable …
mesenchymal stromal cells (MSCs) for nearly every clinical application imaginable …
Advances in pluripotent stem cells: history, mechanisms, technologies, and applications
G Liu, BT David, M Trawczynski, RG Fessler - Stem cell reviews and …, 2020 - Springer
Over the past 20 years, and particularly in the last decade, significant developmental
milestones have driven basic, translational, and clinical advances in the field of stem cell …
milestones have driven basic, translational, and clinical advances in the field of stem cell …
Manufacturing of primed mesenchymal stromal cells for therapy
JQ Yin, J Zhu, JA Ankrum - Nature biomedical engineering, 2019 - nature.com
Mesenchymal stromal cells (MSCs) for basic research and clinical applications are
manufactured and developed as unique cell products by many different manufacturers and …
manufactured and developed as unique cell products by many different manufacturers and …
[HTML][HTML] Secretion of immunoregulatory cytokines by mesenchymal stem cells
D Kyurkchiev, I Bochev… - World journal of stem …, 2014 - ncbi.nlm.nih.gov
According to the minimal criteria of the International Society of Cellular Therapy,
mesenchymal stem cells (MSCs) are a population of undifferentiated cells defined by their …
mesenchymal stem cells (MSCs) are a population of undifferentiated cells defined by their …
Identifying the therapeutic significance of mesenchymal stem cells
The pleiotropic behavior of mesenchymal stem cells (MSCs) has gained global attention due
to their immense potential for immunosuppression and their therapeutic role in immune …
to their immense potential for immunosuppression and their therapeutic role in immune …
Mesenchymal stem cell therapy: hope for patients with systemic lupus erythematosus
A Li, F Guo, Q Pan, S Chen, J Chen, H Liu… - Frontiers in …, 2021 - frontiersin.org
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease. Although previous
studies have demonstrated that SLE is related to the imbalance of cells in the immune …
studies have demonstrated that SLE is related to the imbalance of cells in the immune …
Preconditioning of human mesenchymal stem cells to enhance their regulation of the immune response
Mesenchymal stem cells (MSCs) have attracted the attention of researchers and clinicians
for their ability to differentiate into a number of cell types, participate in tissue regeneration …
for their ability to differentiate into a number of cell types, participate in tissue regeneration …
Pretreated mesenchymal stem cells and their secretome: enhanced immunotherapeutic strategies
Y Su, C Xu, W Cheng, Y Zhao, L Sui… - International journal of …, 2023 - mdpi.com
Mesenchymal stem cells (MSCs) with self-renewing, multilineage differentiation and
immunomodulatory properties, have been extensively studied in the field of regenerative …
immunomodulatory properties, have been extensively studied in the field of regenerative …
[HTML][HTML] Process development for expansion of human mesenchymal stromal cells in a 50 L single-use stirred tank bioreactor
T Lawson, DE Kehoe, AC Schnitzler… - Biochemical …, 2017 - Elsevier
The application of cell-based therapeutics requires development of refined and scalable
culture processes. Stirred tank bioreactors facilitate growth of human mesenchymal stromal …
culture processes. Stirred tank bioreactors facilitate growth of human mesenchymal stromal …