Protein serine/threonine phosphatases (PPPs) are ancient enzymes, with distinct types
conserved across eukaryotic evolution. PPPs are segregated into types primarily on the …

Abstract Protein Phosphatase 2A (PP2A) encompasses a large family of Ser/Thr
phosphatases, consisting of a catalytic C subunit and a structural A subunit that are, in most …

Advances in chemoproteomic technology have revealed covalent interactions between
small molecules and protein nucleophiles, primarily cysteine, on a proteome-wide scale …

Loss of the tumor suppressive activity of the protein phosphatase 2A (PP2A) is associated
with cancer, but the underlying molecular mechanisms are unclear. PP2A holoenzyme …

SUMMARY Protein phosphatase 2A (PP2A) enzymes can suppress tumors, but they are
often inactivated in human cancers overexpressing inhibitory proteins. Here, we identify a …

Protein phosphorylation is a major reversible post‐translational modification. Protein
phosphatases function as 'critical regulators' in signaling networks through …

Protein phosphorylation on serine and threonine residues is a widely distributed post-
translational modification on proteins that acts to regulate their function. Phosphoprotein …

This review presents the accumulating evidence for the roles of protein phosphatase 6 (PP6)
in cell cycle, DNA damage repair, inflammatory signaling, lymphocyte development, virus …

Abstract Protein phosphatase 4 (PP4), one of serine/threonine phosphatases, is involved in
many critical cellular pathways, including DNA damage response (DNA repair, cell cycle …

Objectives High fructose feeding changes fibroblast growth factor 21 (FGF21) regulation.
Lactobacillus rhamnosus GG (LGG) supplementation reduces fructose-induced non …