The role of anti-inflammatory adipokines in cardiometabolic disorders: Moving beyond adiponectin

HN Jung, CH Jung - International Journal of Molecular Sciences, 2021 - mdpi.com
The global burden of obesity has multiplied owing to its rapidly growing prevalence and
obesity-related morbidity and mortality. In addition to the classic role of depositing extra …

Adipokines: Deciphering the cardiovascular signature of adipose tissue

JC Galley, S Singh, WMC Awata, JV Alves… - Biochemical …, 2022 - Elsevier
Obesity and hypertension are intimately linked due to the various ways that the important
cell types such as vascular smooth muscle cells (VSMC), endothelial cells (EC), immune …

Omentin roles in physiology and pathophysiology: an up-to-date comprehensive review

AA Hussein, NA Ahmed, HI Sakr, T Atia… - Archives of Physiology …, 2023 - Taylor & Francis
Omentin (intelectin) was first detected in the visceral omental adipose tissue. It has mainly
two isoforms, omentin-1 and-2, with isoform-1 being the main form in human blood. It …

Human omentin-1 administration ameliorates hypertensive complications without affecting hypertension in spontaneously hypertensive rats

Y Okamura, R Niijima, S Kameshima… - International Journal of …, 2023 - mdpi.com
Hypertension is one of the major risk factors for cardiovascular diseases and is caused by
various abnormalities including the contractility of blood vessels. Spontaneously …

Relationship between circulating serum omentin-1 levels and nascent metabolic syndrome in patients with hypertension

S Cetin Sanlialp, G Nar, R Nar - Journal of Investigative …, 2022 - journals.sagepub.com
The prevalence of metabolic syndrome (MetS) is more common in patients with
hypertension and is associated with an increased risk of target organ damage and/or …

Plasma Biomarkers for Hypertension-Mediated Organ Damage Detection: A Narrative Review

X Liu, M Yang, GYH Lip, G McDowell - Biomedicines, 2024 - mdpi.com
Hypertension (HT) is a disease that poses a serious threat to human health, mediating organ
damage such as the cardiovascular (CV) system, kidneys, central nervous system (CNS) …

Evaluation of Soluble Tumor Necrosis Factor-Like Weak Inducer of Apoptosis, Omentin, and Tumor Necrosis Factor-α in Subjects with Periodontitis and Type 2 …

V Ramasundaram, D Ponnaiyan… - Genetic Testing and …, 2024 - liebertpub.com
Purpose: Periodontal disease worsens glycemic control due to the bidirectional link between
periodontitis and type 2 diabetes mellitus (T2DM), involving inflammatory markers such as …

Circulating Omentin-1 levels and altered iron balance in chronic haemodialysis patients

D Bolignano, E Dounousi, P Presta… - Clinical Kidney …, 2022 - academic.oup.com
Background Iron deficiency is highly prevalent among patients undergoing chronic
haemodialysis (HD) but its correct identification is often problematic as common biomarkers …

Omentin-1 ameliorates pulmonary arterial hypertension by inhibiting endoplasmic reticulum stress through AMPKα signaling

X Deng, H Luo, J He, W Deng… - Clinical and Experimental …, 2024 - Taylor & Francis
Background Endothelial dysfunction of the pulmonary artery contributes to hypoxia-induced
pulmonary arterial hypertension (PAH). Omentin-1, as a novel adipocytokine, plays an …

[HTML][HTML] Association between circulating omentin-1 levels and aortic valve sclerosis

M Dogdus, F Dindas, Y Cekici, A Yildirim… - Acta Cardiologica …, 2022 - ncbi.nlm.nih.gov
Background Aortic valve sclerosis (AVS) is characterized by thickening of the valve leaflets
accompanied by increased echogenicity and calcification without significant limitations in …