Multi-omics approaches have developed as a profitable technique for plant systems, a
popular method in medical and biological sciences underlining the necessity to outline new …

Metabolomics and lipidomics have an increasingly pivotal role in drug discovery and
development. In the context of drug discovery, monitoring changes in the levels or …

Alveolar epithelial type II (AEC2) cells strictly regulate lipid metabolism to maintain surfactant
synthesis. Loss of AEC2 cell function and surfactant production are implicated in the …

Background Moderately raised serum bilirubin levels are associated with lower rates of lung
cancer, particularly among smokers. It is not known whether these relationships reflect …

Heterogeneous reaction of gas phase NO2 with atmospheric humic-like substances (HULIS)
is potentially an important source of volatile organic compounds (VOCs) including nitrogen …

The emerging high-throughput technologies have led to the shift in the design of
translational medicine projects towards collecting multi-omics patient samples and …

The alveolar epithelium is covered by a non-cellular layer consisting of an aqueous
hypophase topped by pulmonary surfactant, a lipo-protein mixture with surface-active …

Insights into the modes of action (MoAs) of xenobiotics are of utmost importance for the
definition of adverse outcome pathways (AOPs), which are essential for a mechanism-based …

Proteins are the ultimate product of gene expression. As they hinge between gene
transcription and phenotype, they offer a more realistic perspective of toxicopathic effects …

Cigarette smoking is a major preventable cause of morbidity and mortality. While quitting
smoking is the best option, switching from cigarettes to non-combustible alternatives (NCAs) …