Light-triggered photodynamic nanomedicines for overcoming localized therapeutic efficacy in cancer treatment
Photodynamic nanomedicines have significantly enhanced the therapeutic efficacy of
photosensitizers (PSs) by overcoming critical limitations of PSs such as poor water solubility …
photosensitizers (PSs) by overcoming critical limitations of PSs such as poor water solubility …
Recent progress in multifunctional conjugated polymer nanomaterial-based synergistic combination phototherapy for microbial infection theranostics
P Manivasagan, J Kim, ES Jang - Coordination Chemistry Reviews, 2022 - Elsevier
Microbial infection is a critical public health problem, owing to its strong infectivity and high
risk of mortality. Multi-antibiotic resistant pathogens reduce the efficacy of commercial …
risk of mortality. Multi-antibiotic resistant pathogens reduce the efficacy of commercial …
Enzyme-responsive double-locked photodynamic molecular beacon for targeted photodynamic anticancer therapy
An advanced photodynamic molecular beacon (PMB) was designed and synthesized, in
which a distyryl boron dipyrromethene (DSBDP)-based photosensitizer and a Black Hole …
which a distyryl boron dipyrromethene (DSBDP)-based photosensitizer and a Black Hole …
Specific activation of photosensitizer with extrinsic enzyme for precisive photodynamic therapy
Delivery of functional proteins into the intracellular space has been a challenging task that
could lead to a myriad of therapeutic applications. We report herein a novel bioconjugation …
could lead to a myriad of therapeutic applications. We report herein a novel bioconjugation …
Trial watch: an update of clinical advances in photodynamic therapy and its immunoadjuvant properties for cancer treatment
M Penetra, LG Arnaut, LC Gomes-da-Silva - 2023 - Taylor & Francis
Photodynamic therapy (PDT) is a medical treatment used to target solid tumors, where the
administration of a photosensitizing agent and light generate reactive oxygen species …
administration of a photosensitizing agent and light generate reactive oxygen species …
EGFR-targeted photodynamic therapy
L Ulfo, PE Costantini, M Di Giosia, A Danielli… - Pharmaceutics, 2022 - mdpi.com
The epidermal growth factor receptor (EGFR) plays a pivotal role in the proliferation and
metastatization of cancer cells. Aberrancies in the expression and activation of EGFR are …
metastatization of cancer cells. Aberrancies in the expression and activation of EGFR are …
Design and Development of a Bioorthogonal, Visualizable and Mitochondria‐Targeted Hydrogen Sulfide (H2S) Delivery System
Y Chen, R Zhao, C Tang, C Zhang, W Xu… - Angewandte …, 2022 - Wiley Online Library
Hydrogen sulfide (H2S) is an important endogenous gasotransmitter, but the targeted
delivery and real‐time feedback of exogenous H2S are still challenging. With the aid of …
delivery and real‐time feedback of exogenous H2S are still challenging. With the aid of …
Gel formulations for topical treatment of skin cancer: a review
Skin cancer, with all its variations, is the most common type of cancer worldwide.
Chemotherapy by topical application is an attractive strategy because of the ease of …
Chemotherapy by topical application is an attractive strategy because of the ease of …
Unraveling the pivotal role of atropisomerism for cellular internalization
C Donohoe, FA Schaberle… - Journal of the …, 2022 - ACS Publications
The intrinsic challenge of large molecules to cross the cell membrane and reach intracellular
targets is a major obstacle for the development of new medicines. We report how rotation …
targets is a major obstacle for the development of new medicines. We report how rotation …
Combinatorial therapeutic approaches with nanomaterial-based photodynamic cancer therapy
Photodynamic therapy (PDT), in which a light source is used in combination with a
photosensitizer to induce local cell death, has shown great promise in therapeutically …
photosensitizer to induce local cell death, has shown great promise in therapeutically …