Chronic (continuous, non-interrupted) hypoxia and cycling (intermittent, transient) hypoxia
are two types of hypoxia occurring in malignant tumors. They are both associated with the …

The resolution of inflammation has emerged as a critical endogenous process that protects
host tissues from prolonged or excessive inflammation that can become chronic. Failure of …

Natural product compounds have recently attracted significant attention from the scientific
community for their potent effects against inflammation-driven diseases, including cancer. A …

Colorectal cancer (CRC) is the third most common cancer and the fourth most common
cause of cancer-related death. Most cases of CRC are detected in Western countries, with its …

Inflammation is the principal response invoked by the body to address injuries. Despite
inflammation constituting a crucial component of tissue repair, it is well known that …

PARP-1 (poly (ADP-ribose)-polymerase 1), mainly known for its protective role in DNA
repair, also regulates inflammatory processes. Notably, defects in DNA repair and chronic …

Natural compounds, in recent years, have attracted significant attention for their use in the
prevention and treatment of diverse chronic diseases as they are devoid of major toxicities …

Hesperidin belongs to flavanones class of flavonoids and is known to possess broad-
spectrum applicability to prevent dreadful diseases such as cardiovascular disease …

Introduction Epithelial-mesenchymal transition (EMT) is a process of transdifferentiation
where epithelial cells attain mesenchymal phenotype to gain invasive properties and thus …

Signal transducer and activator of transcription 3 (STAT3) is one of the crucial transcription
factors, responsible for regulating cellular proliferation, cellular differentiation, migration …