Collagen is a ubiquitous biomaterial in vertebrate animals. Although each of its 28 subtypes
contributes to the functions of many different tissues in the body, most studies on collagen or …

Proteins are involved in many biological processes. Misfolded, truncated, or mutated
proteins as well as over-or underexpressed proteins have been implicated in many …

Derived from the term exposure, the exposome is an omic-scale characterization of the
nongenetic drivers of health and disease. With the genome, it defines the phenome of an …

Nanoscale objects, whether of biologic origin or synthetically created, are being developed
into devices for a variety of bionanotechnology diagnostic and pharmaceutical applications …

Many chronic conditions such as cancer, chronic obstructive pulmonary disease, type-2
diabetes, obesity, peripheral/coronary artery disease and auto-immune diseases are …

Over the last decade there has been an enormous expansion of research focused on
defining the role of inflammation in aging, age-related diseases, disability, and frailty. The …

Conceptual and methodological issues relevant to cytokine an... : Current Opinion in
Clinical Nutrition & Metabolic Care Conceptual and methodological issues relevant to …

This review paper describes a new technology, mass cytometry, that addresses applications
typically run by flow cytometer analyzers, but extends the capability to highly multiparametric …

To increase disease survival rates, there is a vital need for diagnosis at very preliminary
stages. Then, low concentrations of biomarkers are present which must be effectively …

Background: A complex network of biological mediators underlies the clinical syndrome of
sepsis. The nonspecific physiologic criteria of sepsis syndrome or the systemic inflammatory …