Neurological insults, such as congenital blindness, deafness, amputation, and stroke, often
result in surprising and impressive behavioural changes. Cortical reorganisation, which …

▪ Abstract It has been clear for almost two decades that cortical representations in adult
animals are not fixed entities, but rather, are dynamic and are continuously modified by …

▪ Abstract Neuronal circuits are shaped by experience during critical periods of early
postnatal life. The ability to control the timing, duration, and closure of these heightened …

▪ Abstract Many neurons in the mammalian central nervous system communicate through
electrical synapses, defined here as gap junction–mediated connections. Electrical …

Nichts fürchten wir so sehr wie unsere ureigenen Ängste. Und doch sind es gerade unsere
Ängste in all ihren Schattierungen, die unsere geistige und emotionale Entwicklung in …

Neural plasticity--the brain's ability to change in response to normal developmental
processes, experience, and injury--is a critically important phenomenon for both …

The cerebral cortex, occupying over 70 percent of our brain mass, is key to any
understanding of the workings--and disorders--of the human brain. offering a …

The arealization of the mammalian cortex is believed to be controlled by a combination of
intrinsic factors that are expressed in the cortex, and external signals, some of which are …

Although maturing neurons undergo a precipitous decline in the expression of genes
associated with developmental axon growth, structural changes in axon arbors occur in the …

Recently, we have identified a novel form of synaptic plasticity that acts to stabilize
neocortical firing rates by scaling the quantal amplitude of AMPA-mediated synaptic inputs …