Signaling pathways involved in paraquat-induced pulmonary toxicity: Molecular mechanisms and potential therapeutic drugs
X Liu, H Yang, Z Liu - International Immunopharmacology, 2022 - Elsevier
Paraquat poisoning is a severe health problem globally, particularly in developing countries.
Due to its severe toxicity, the mortality rate of paraquat poisoning is greatly higher than other …
Due to its severe toxicity, the mortality rate of paraquat poisoning is greatly higher than other …
The herbicide paraquat-induced molecular mechanisms in the development of acute lung injury and lung fibrosis
Abstract The herbicide paraquat (PQ; 1, 1'-dimethyl-4, 4'-bipyridylium dichloride) is a highly
toxic organic heterocyclic herbicide that has been widely used in agricultural settings. Since …
toxic organic heterocyclic herbicide that has been widely used in agricultural settings. Since …
[HTML][HTML] Hepatoprotective effect of berberine against methotrexate induced liver toxicity in rats
Hepatotoxicity is one of the major side effects of methotrexate (MTX), which restricts the
clinical use of this drug. Berberine (BBR) is a natural compound with multiple …
clinical use of this drug. Berberine (BBR) is a natural compound with multiple …
Therapeutic potential of traditional Chinese medicine for interstitial lung disease
YM Zhou, XR Dong, D Xu, J Tang, YL Cui - Journal of ethnopharmacology, 2024 - Elsevier
Ethnopharmacological relevance Interstitial lung disease (ILD) is a chronic lung dysfunction
disease with a poor prognosis and poor recovery. The clinically used therapeutic drugs …
disease with a poor prognosis and poor recovery. The clinically used therapeutic drugs …
[HTML][HTML] Evaluating the protective effects of melatonin on di (2-ethylhexyl) phthalate-induced testicular injury in adult mice
Abstract Objective Di (2-ethylhexyl) phthalate (DEHP) is a common phthalate derivative,
interfering with normal function of reproductive system. The present study evaluated effects …
interfering with normal function of reproductive system. The present study evaluated effects …
[HTML][HTML] Aspirin eugenol ester ameliorates paraquat-induced oxidative damage through ROS/p38-MAPK-mediated mitochondrial apoptosis pathway
ZD Zhang, YJ Yang, XW Liu, Z Qin, SH Li, JY Li - Toxicology, 2021 - Elsevier
Paraquat (PQ) is an effective and commercially important herbicide that is widely used
worldwide. However, PQ is highly toxic and can cause various complications and acute …
worldwide. However, PQ is highly toxic and can cause various complications and acute …
Natural product-based potential therapeutic interventions of pulmonary fibrosis
Pulmonary fibrosis (PF) is a disease-refractive lung condition with an increased rate of
mortality. The potential factors causing PF include viral infections, radiation exposure, and …
mortality. The potential factors causing PF include viral infections, radiation exposure, and …
The role of natural products in the prevention and treatment of pulmonary fibrosis: a review
L Wang, S Li, Y Yao, W Yin, T Ye - Food & function, 2021 - pubs.rsc.org
Pulmonary fibrosis is an incurable end-stage lung disease and remains a global public
health problem. Although there have been some breakthroughs in understanding the …
health problem. Although there have been some breakthroughs in understanding the …
[HTML][HTML] Berberis vulgaris and its constituent berberine as antidotes and protective agents against natural or chemical toxicities
N Mohammadzadeh, S Mehri… - Iranian journal of basic …, 2017 - ncbi.nlm.nih.gov
Berberis vulgaris L (B. vulgaris) and its main constituent berberine have been used in
traditional medicine for a long time. This medicinal plant and berberine have many …
traditional medicine for a long time. This medicinal plant and berberine have many …
Immunological axis of berberine in managing inflammation underlying chronic respiratory inflammatory diseases
XN Tew, NJX Lau, DK Chellappan… - Chemico-biological …, 2020 - Elsevier
Inflammatory responses play a remarkable role in the mechanisms of acute and chronic
respiratory diseases such as chronic obstructive pulmonary disease (COPD), asthma …
respiratory diseases such as chronic obstructive pulmonary disease (COPD), asthma …