This review is focused on free-electron lasers (FELs) in the hard to soft x-ray regime. The
aim is to provide newcomers to the area with insights into: the basic physics of FELs, the …

Research opportunities and techniques are reviewed for the application of hard x-ray pulsed
free-electron lasers (XFEL) to structural biology. These include the imaging of protein …

X-ray lasers offer new capabilities in understanding the structure of biological systems,
complex materials and matter under extreme conditions,,,. Very short and extremely bright …

We present a proof-of-concept three-dimensional reconstruction of the giant mimivirus
particle from experimentally measured diffraction patterns from an x-ray free-electron laser …

There exists a conspicuous gap of knowledge about the organization of life at mesoscopic
levels. Ultra-fast coherent diffractive imaging with X-ray free-electron lasers can probe …

We overcome two of the most daunting challenges in single-particle diffractive imaging:
collecting many high-quality diffraction patterns on a small amount of sample and separating …

We use extremely bright and ultrashort pulses from an x-ray free-electron laser (XFEL) to
measure correlations in x rays scattered from individual bioparticles. This allows us to go …

The open-source PyNX toolkit has been extended to provide tools for coherent X-ray
imaging data analysis and simulation. All calculations can be executed on graphical …

Single particle diffractive imaging data from Rice Dwarf Virus (RDV) were recorded using the
Coherent X-ray Imaging (CXI) instrument at the Linac Coherent Light Source (LCLS). RDV …

The possibility of imaging single proteins constitutes an exciting challenge for x-ray lasers.
Despite encouraging results on large particles, imaging small particles has proven to be …