Clinical and diagnostic implications of Alzheimer's disease copathology in Lewy body disease

L Barba, S Abu-Rumeileh, H Barthel, F Massa… - Brain, 2024 - academic.oup.com
Concomitant Alzheimer's disease (AD) pathology is a frequent event in the context of Lewy
body disease (LBD), occurring in approximately half of all cases. Evidence shows that LBD …

Dementia prevention and treatment: a narrative review

DB Reuben, S Kremen, DT Maust - JAMA Internal Medicine, 2024 - jamanetwork.com
Importance Dementia affects 10% of those 65 years or older and 35% of those 90 years or
older, often with profound cognitive, behavioral, and functional consequences. As the baby …

18F‐Florzolotau PET Imaging Unveils Tau Pathology in Dementia with Lewy Bodies

G Tang, JY Lu, XY Li, RX Yao, YJ Yang… - Movement …, 2024 - Wiley Online Library
Abstract Background Dementia with Lewy bodies (DLB) commonly exhibits a complex
neuropathology, sharing characteristics with Alzheimer's disease (AD), including tau …

Diagnostic performance of light reflex pupillometry in Alzheimer's disease

MH Gramkow, FK Clemmensen… - Alzheimer's & …, 2024 - Wiley Online Library
Easily applied diagnostic tools such as digital biomarkers for Alzheimer's disease (AD) are
urgently needed due to the recent approval of disease‐modifying therapies. We aimed to …

Characteristics associated with progression to probable dementia with Lewy bodies in a cohort with very late-onset psychosis

LL Gibson, C Mueller, R Stewart… - Psychological Medicine, 2024 - cambridge.org
BackgroundVery late-onset psychosis (VLOP) is associated with higher rates of dementia
but the proportion who develop dementia with Lewy bodies (DLB) is unknown. We aimed to …

Designing and Formulation of Nanocarriers for “Alzheimer's and Parkinson's” Early Detection and Therapy

J Abujamai, R Satar, SA Ansari - CNS & Neurological Disorders …, 2024 - benthamdirect.com
The potential of nanotechnology in advancing the diagnosis and treatment of
neurodegenerative diseases is explored in this comprehensive literature review. The …

Plasma pTau181 reveals a pathological signature that predicts cognitive outcomes in Lewy body disease

C Abdelnour, CB Young, M Shahid‐Besanti… - Annals of …, 2024 - Wiley Online Library
Objective To determine whether plasma phosphorylated‐Tau181 (pTau181) could be used
as a diagnostic biomarker of concurrent Alzheimer's disease neuropathologic change …

Separating dementia with Lewy bodies from Alzheimer's disease dementia using a volumetric MRI classifier

AM van Gils, AJ Tolonen, HFM Rhodius-Meester… - European …, 2024 - Springer
Abstract Objectives Distinguishing dementia with Lewy bodies (DLB) from Alzheimer's
disease (AD) dementia, particularly in patients with DLB and concomitant AD pathology …

Neuroimaging Findings of Psychosis in Alzheimer's Disease: A Systematic Review

F Nabizadeh, S Sheykhlou, S Mahmoodi… - Brain and …, 2025 - Wiley Online Library
Background Previous studies on neuroimaging findings in Alzheimer's disease (AD) patients
with hallucinations and delusions have yielded inconsistent results. We aimed to …

Updates in Fluid, Tissue, and Imaging Biomarkers for Dementia with Lewy Bodies and Implications for Biologically Based Disease Definitions

SK Holden - Current Treatment Options in Neurology, 2024 - Springer
Continued validation and technical harmonization efforts will be needed prior to widespread
clinical application of new Lewy body biomarkers. Combining existing and novel DLB and …