Skin application of pharmaceutical products is one of the methods used for drug
administration. The problem of limited drug penetration via topical application makes …

Assessing the bioavailability of drug molecules at the site of action provides better insight
into the efficiency of a dosage form. However, determining drug concentration in the skin …

Three acyclovir complexes including one salt with maleic acid, and two cocrystals with
fumaric acid and glutaric acid, were prepared. The results of powder dissolution and in vitro …

Proteins and peptides are increasingly important therapeutics for the treatment of severe
and complex diseases like cancer or autoimmune diseases due to their high specificity and …

Alzheimer's disease (AD) is the most common type of senile dementia, characterized by
cognitive deficits related to degeneration of cholinergic neurons. The first anti-Alzheimer …

Cocrystals have gained attention in the pharmaceutical industry due to their ability to
improve solubility, stability, in vitro dissolution rate, and bioavailability of poorly soluble …

The aim of the study was to develop and optimize Piroxicam transdermal gel formulation
using three-factor, three-level Box–Behnken design by deriving a second-order polynomial …

Liposomes containing a certain amount of ethanol are often referred to in the literature as
ethosomes. Liposomes vary in size from 25 nm to 25,000 nm. Ethosomes are defined as …

Background Despite promising results, laser-assisted drug delivery (LADD) is not yet
considered as standard therapies and published data rely mainly on laboratory tests, animal …

Cefixime is a third-generation cephalosporin antibiotic with poor solubility and permeability.
The aim was to compared between Dry Grinding (DG) and Liquid-Assisted Grinding (LAG) …