Volumetric muscle loss (VML) is a devastating loss of muscle tissue that overwhelms the
native regenerative properties of skeletal muscle and results in lifelong functional deficits …

Millions of Americans suffer from skeletal muscle injuries annually that can result in
volumetric muscle loss (VML), where extensive musculoskeletal damage and tissue loss …

Although skeletal muscle is highly regenerative following injury or disease, endogenous self‐
regeneration is severely impaired in conditions of volume traumatic muscle loss …

The musculoskeletal (MS) system consists of bone, cartilage, tendon, ligament, and skeletal
muscle, which forms the basic framework of the human body. This system plays a vital role in …

Skeletal muscle is a complex tissue composed of multinucleated myofibers responsible for
force generation that are supported by multiple cell types. Many severe and lethal disorders …

Recent years have witnessed significant progress in skeletal muscle tissue regeneration.
Numerous bioengineering approaches have been implemented to construct in vitro skeletal …

Tissue engineering strategies to treat patients with volumetric muscle loss (VML) aim to
recover the structure and contractile function of lost muscle tissue. Here, we assessed the …

Extreme loss of skeletal muscle overwhelms the natural regenerative capability of the body,
results in permanent disability and substantial economic burden. Current surgical …

Repair of injured skeletal muscle is a sophisticated process that uses immune, muscle,
perivascular, and neural cells. In acute injury, the robust endogenous repair process can …

Tissue scaffolds are essential in tissue engineering approaches as they provide a tissue-
mimicking environment for cells, with the aim to promote cell proliferation, cell differentiation …