A review: Pharmacological aspects of metal based 1, 2, 4-triazole derived Schiff bases

W Zafar, SH Sumrra, ZH Chohan - European journal of medicinal chemistry, 2021 - Elsevier
Clinical reports have highlighted the radical increase of antibiotic resistance. As a result,
multidrug resistance has emerged as a serious threat to human health. Many organic …

Inhibitory potential of nitrogen, oxygen and sulfur containing heterocyclic scaffolds against acetylcholinesterase and butyrylcholinesterase

RJ Obaid, N Naeem, EU Mughal, MM Al-Rooqi… - RSC …, 2022 - pubs.rsc.org
Heterocycles are the key structures in organic chemistry owing to their immense applications
in the biological, chemical, and pharmaceutical fields. Heterocyclic compounds perform …

Synthesis, characterization, pharmacological screening, molecular docking, DFT, MESP, ADMET studies of transition metal (II) chelates of bidentate schiff base ligand

N Dawar, J Devi, B Kumar, A Dubey - Inorganic Chemistry Communications, 2023 - Elsevier
The death causing infectious diseases are increased very rapidly, therefore, to find out a
significant agent for these ailments, a family of four transition metal complexes were …

A review on the biomedical efficacy of transition metal triazole compounds

SH Sumrra, W Zafar, M Imran… - Journal of Coordination …, 2022 - Taylor & Francis
From the apocalyptic era of antibiotic resistance, the scientific community around the world is
engaged in designing and developing metal-based compounds to inhibit and control …

Correlating the charge transfer efficiency of metallic sulfa-isatins to design efficient NLO materials with better drug designs

S Noreen, SH Sumrra - Biometals, 2022 - Springer
The present study presents synthesis, characterization and first principle studies on metal
chelates,(1–12), of sulfonamide-isatin reacted ligands (S 1–S 3). All the products were …

Aminothiazole-linked metal chelates: synthesis, density functional theory, and antimicrobial studies with antioxidant correlations

S Noreen, SH Sumrra - ACS omega, 2021 - ACS Publications
During the current study, the new aminothiazole Schiff base ligands (S1) and (S2) were
designed by reacting 1, 3-thiazol-2-amine and 6-ethoxy-1, 3-benzothiazole-2-amine …

Facile synthesis, spectroscopic evaluation and antimicrobial screening of metal endowed triazole compounds

SH Sumrra, W Zafar, H Javed, M Zafar, MZ Hussain… - Biometals, 2021 - Springer
The scientific interest in developing new complexes as inhibitors of bacterial biofilm related
infections is constantly rising. The present work describes the chemical synthesis, structural …

Synthesis, characterization, molecular docking and network pharmacology of bioactive metallic sulfonamide-isatin ligands against promising drug targets

S Noreen, SH Sumrra, ZH Chohan, G Mustafa… - Journal of Molecular …, 2023 - Elsevier
A series of sulfonamide and isatin based Schiff bases,(S 1) and (S 2), and their metal (Co
2+, Ni 2+, Cu 2+ and Zn 2+) complexes (1)-(8) were synthesized and characterized by …

Designing of some novel Pd (II), Ni (II) and Fe (III) complexes: Synthesis, structural elucidation, biomedical applications, DFT and docking approaches against Covid …

AM Abu-Dief, MA Said, O Elhady, N Alahmadi… - Inorganic Chemistry …, 2023 - Elsevier
A new class of bio-active Pd (II), Ni (II) and Fe (III) complexes [Pd (L)(COOCH 3) 2](H 2 O)
2,[Ni (L) 2 (NO 3) 2](H 2 O), and [Fe (L) 2 (NO 3) 2](NO 3)(H 2 O) 2 have been constituted by …

DFT-guided structural modeling of end-group acceptors at Y123 core for sensitizers as high-performance organic solar dyes and NLO responses

AU Hassan, SH Sumrra, M Zafar, A Mohyuddin… - Journal of Molecular …, 2023 - Springer
Context The organic solar cells (OSCs) are being developed with the goal of improving their
photovoltaic capabilities. Here, utilizing computational methods, six new nonfullerene …