Comparison of glioblastoma (GBM) molecular classification methods
Glioblastoma (GBM) is the most aggressive and common form of brain cancer in adults.
GBM is characterized by poor survival and remarkably high tumors heterogeneity (both …
GBM is characterized by poor survival and remarkably high tumors heterogeneity (both …
Tissue factor is a critical regulator of radiation therapy-induced glioblastoma remodeling
Radiation therapy (RT) provides therapeutic benefits for patients with glioblastoma (GBM),
but inevitably induces poorly understood global changes in GBM and its microenvironment …
but inevitably induces poorly understood global changes in GBM and its microenvironment …
Target-based anticancer indole derivatives for the development of anti-glioblastoma agents
S Salerno, E Barresi, E Baglini, V Poggetti… - Molecules, 2023 - mdpi.com
Glioblastoma (GBM) is the most aggressive and frequent primary brain tumor, with a poor
prognosis and the highest mortality rate. Currently, GBM therapy consists of surgical …
prognosis and the highest mortality rate. Currently, GBM therapy consists of surgical …
The mitotic kinesin KIF11 is a driver of invasion, proliferation, and self-renewal in glioblastoma
The proliferative and invasive nature of malignant cancers drives lethality. In glioblastoma,
these two processes are presumed mutually exclusive and hence termed “go or grow.” We …
these two processes are presumed mutually exclusive and hence termed “go or grow.” We …
Genome-wide CRISPR-Cas9 screens reveal loss of redundancy between PKMYT1 and WEE1 in glioblastoma stem-like cells
CM Toledo, Y Ding, P Hoellerbauer, RJ Davis… - Cell reports, 2015 - cell.com
To identify therapeutic targets for glioblastoma (GBM), we performed genome-wide CRISPR-
Cas9 knockout (KO) screens in patient-derived GBM stem-like cells (GSCs) and human …
Cas9 knockout (KO) screens in patient-derived GBM stem-like cells (GSCs) and human …
BUB1 drives the occurrence and development of bladder cancer by mediating the STAT3 signaling pathway
N Jiang, Y Liao, M Wang, Y Wang, K Wang… - Journal of Experimental …, 2021 - Springer
Background The incidence of bladder urothelial carcinoma (UC), a common malignancy of
the urinary tract, is approximately three times higher in men than in women. High expression …
the urinary tract, is approximately three times higher in men than in women. High expression …
BUB1B and circBUB1B_544aa aggravate multiple myeloma malignancy through evoking chromosomal instability
X Tang, M Guo, P Ding, Z Deng, M Ke, Y Yuan… - … and Targeted Therapy, 2021 - nature.com
Multiple myeloma (MM) is an incurable plasma cell malignancy in the bone marrow
characterized by chromosome instability (CIN), which contributes to the acquisition of …
characterized by chromosome instability (CIN), which contributes to the acquisition of …
[HTML][HTML] ZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor-initiating cell state
Glioblastoma (GBM) harbors subpopulations of therapy-resistant tumor-initiating cells (TICs)
that are self-renewing and multipotent. To understand the regulation of the TIC state, we …
that are self-renewing and multipotent. To understand the regulation of the TIC state, we …
Efficient CRISPR/Cas9-assisted gene targeting enables rapid and precise genetic manipulation of mammalian neural stem cells
RB Bressan, PS Dewari, M Kalantzaki… - …, 2017 - journals.biologists.com
Mammalian neural stem cell (NSC) lines provide a tractable model for discovery across stem
cell and developmental biology, regenerative medicine and neuroscience. They can be …
cell and developmental biology, regenerative medicine and neuroscience. They can be …
Supramolecularly enabled pH-triggered drug action at tumor microenvironment potentiates nanomedicine efficacy against glioblastoma
The crucial balance of stability in blood-circulation and tumor-specific delivery has been
suggested as one of the challenges for effective bench-to-bedside translation of …
suggested as one of the challenges for effective bench-to-bedside translation of …