Understanding health inequalities through the lens of social epigenetics
Longstanding racial/ethnic inequalities in morbidity and mortality persist in the United States.
Although the determinants of health inequalities are complex, social and structural factors …
Although the determinants of health inequalities are complex, social and structural factors …
A systematic review of childhood maltreatment and DNA methylation: candidate gene and epigenome-wide approaches
Childhood maltreatment is a major risk factor for chronic and severe mental and physical
health problems across the lifespan. Increasing evidence supports the hypothesis that …
health problems across the lifespan. Increasing evidence supports the hypothesis that …
[HTML][HTML] Childhood maltreatment and DNA methylation: A systematic review
DNA methylation (DNAm)–an epigenetic process that regulates gene expression–may
represent a mechanism for the biological embedding of early traumatic experiences …
represent a mechanism for the biological embedding of early traumatic experiences …
Adversity exposure during sensitive periods predicts accelerated epigenetic aging in children
Objectives Exposure to adversity has been linked to accelerated biological aging, which in
turn has been shown to predict numerous physical and mental health problems. In recent …
turn has been shown to predict numerous physical and mental health problems. In recent …
High social status males experience accelerated epigenetic aging in wild baboons
Aging, for virtually all life, is inescapable. However, within populations, biological aging rates
vary. Understanding sources of variation in this process is central to understanding the …
vary. Understanding sources of variation in this process is central to understanding the …
Early-life adversity accelerates child and adolescent development
J Belsky - Current Directions in Psychological Science, 2019 - journals.sagepub.com
Most developmental work regards adverse developmental experiences as forces that
undermine well-being. Here, I present an alternative—or complementary—view …
undermine well-being. Here, I present an alternative—or complementary—view …
A systematic review and meta-analysis of environmental, lifestyle, and health factors associated with DNA methylation age
J Ryan, J Wrigglesworth, J Loong… - The Journals of …, 2020 - academic.oup.com
DNA methylation (DNAm) algorithms of biological age provide a robust estimate of an
individual's chronological age and can predict their risk of age-related disease and mortality …
individual's chronological age and can predict their risk of age-related disease and mortality …
How to slow down the ticking clock: age-associated epigenetic alterations and related interventions to extend life span
Epigenetic alterations pose one major hallmark of organismal aging. Here, we provide an
overview on recent findings describing the epigenetic changes that arise during aging and …
overview on recent findings describing the epigenetic changes that arise during aging and …
Child maltreatment and long-term physical and mental health outcomes: an exploration of biopsychosocial determinants and implications for prevention
Child maltreatment rates remain unacceptably high and rates are likely to escalate as
COVID-related economic problems continue. A comprehensive and evidence-building …
COVID-related economic problems continue. A comprehensive and evidence-building …
Early life adversity and age acceleration at mid-life and older ages indexed using the next-generation GrimAge and Pace of Aging epigenetic clocks
Objective This retrospective cross-sectional study was designed to explore whether the
experience of childhood adversity was associated with epigenetic age acceleration in mid …
experience of childhood adversity was associated with epigenetic age acceleration in mid …