A growing body of evidence has emerged demonstrating a pathological link between
oxidative stress and schizophrenia. This evidence identifies oxidative stress as a …

A good nutritional status is important for maintaining normal body function and preventing or
mitigating the dysfunction induced by internal or external factors. Nutritional deficiencies …

Intervention at the earliest illness stage, in ultra or clinical high-risk individuals, or indicated
prevention, currently represents the most promising strategy to ameliorate, delay or prevent …

Psychiatric disorders affect 970 million people worldwide, representing a significant source
of disability. Although the underlying neurobiological traits for these disorders are not fully …

Redox biology and immune signaling play major roles in the body, including in brain
function. A rapidly growing literature also suggests that redox and immune abnormalities are …

Current silo-based diagnostic systems for mental disorders lack utility and fail to fulfil a
fundamental purpose of diagnosis: to guide treatment planning and predict outcomes …

Importance Clinical trials have not established the optimal type, sequence, and duration of
interventions for people at ultrahigh risk of psychosis. Objective To determine the …

Preliminary evidence indicates beneficial effects of omega-3 polyunsaturated fatty acids
(PUFAs) in early psychosis. The present study investigates the molecular mechanism of …

Polyunsaturated fatty acids (PUFAs) may be pertinent to the development of mental
disorders, for example via modulation of inflammation and synaptogenesis. We wished to …

Background Schizophrenia is a serious long-term psychotic disorder marked by positive and
negative symptoms, severe behavioral problems and cognitive function deficits. The cause …