Direct olefinic C–H functionalization represents the ideal way of introducing an alkenyl
group into organic molecules. A well-known process is the Heck reaction, which involves …

Abstract α‐Carbonyl alkyl bromides are powerful reactive species for the formation of carbon–
carbon bonds. Strategies relying on intermolecular C− H functionalization and cross …

A copper-catalyzed intermolecular three-component asymmetric radical 1, 2-
carboalkynylation of alkenes has been developed, providing straightforward access to …

The Heck reaction is one of the most reliable and useful strategies for the construction of C–
C bonds in organic synthesis. However, in contrast to the well-established aryl Heck …

A new type of intermolecular alkylative olefination of unactivated olefins and alkyl halides
has been realized for the first time. This copper-promoted Heck-type reaction employs a …

The development of mild and practical methods for the γ-arylation of carbonyl compounds is
an ongoing challenge in organic synthesis. The first formal γ-arylation of carbonyl …

A three‐component alkoxycyanomethylation of alkenes is achieved using the iridium
photoredox catalyst [fac‐Ir (ppy) 3]. This catalytic radical difunctionalization accomplishes …

The ability of iron to controllably generate alkyl radicals from alkyl halides as a key step in
atom transfer radical polymerization (ATRP) has been adapted to facilitate a formal Heck …

Visible-light photoredox catalysis enables the vinylation and allylation of electrophilic
radicals with readily available potassium trifluoroborate reagents. The processes show good …

A Cu-catalyzed cascade annulation of enynals with alkenyl or alkynyl α-bromocarbonyls for
the synthesis of various cyclohexenone-fused polycyclic compounds is described. Up to six …