Growth and division of the peptidoglycan matrix
PDA Rohs, TG Bernhardt - Annual review of microbiology, 2021 - annualreviews.org
Most bacteria are surrounded by a peptidoglycan cell wall that defines their shape and
protects them from osmotic lysis. The expansion and division of this structure therefore plays …
protects them from osmotic lysis. The expansion and division of this structure therefore plays …
Bacterial cell wall quality control during environmental stress
EA Mueller, PA Levin - MBio, 2020 - Am Soc Microbiol
Single-celled organisms must adapt their physiology to persist and propagate across a wide
range of environmental conditions. The growth and division of bacterial cells depend on …
range of environmental conditions. The growth and division of bacterial cells depend on …
The architecture of the Gram-positive bacterial cell wall
The primary structural component of the bacterial cell wall is peptidoglycan, which is
essential for viability and the synthesis of which is the target for crucial antibiotics …
essential for viability and the synthesis of which is the target for crucial antibiotics …
Cell wall synthesis and remodelling dynamics determine division site architecture and cell shape in Escherichia coli
PP Navarro, A Vettiger, VY Ananda, PM Llopis… - Nature …, 2022 - nature.com
The bacterial division apparatus catalyses the synthesis and remodelling of septal
peptidoglycan (sPG) to build the cell wall layer that fortifies the daughter cell poles …
peptidoglycan (sPG) to build the cell wall layer that fortifies the daughter cell poles …
Peptidoglycan: structure, synthesis, and regulation
Peptidoglycan is a defining feature of the bacterial cell wall. Initially identified as a target of
the revolutionary beta-lactam antibiotics, peptidoglycan has become a subject of much …
the revolutionary beta-lactam antibiotics, peptidoglycan has become a subject of much …
Class-A penicillin binding proteins do not contribute to cell shape but repair cell-wall defects
Cell shape and cell-envelope integrity of bacteria are determined by the peptidoglycan cell
wall. In rod-shaped Escherichia coli, two conserved sets of machinery are essential for cell …
wall. In rod-shaped Escherichia coli, two conserved sets of machinery are essential for cell …
Growth rate is modulated by monitoring cell wall precursors in Bacillus subtilis
How bacteria link their growth rate to external nutrient conditions is unknown. To investigate
how Bacillus subtilis cells alter the rate at which they expand their cell walls as they grow …
how Bacillus subtilis cells alter the rate at which they expand their cell walls as they grow …
Antibiotic resistance via bacterial cell shape-shifting
Bacteria have evolved to develop multiple strategies for antibiotic resistance by effectively
reducing intracellular antibiotic concentrations or antibiotic binding affinities, but the role of …
reducing intracellular antibiotic concentrations or antibiotic binding affinities, but the role of …
Diversification of division mechanisms in endospore-forming bacteria revealed by analyses of peptidoglycan synthesis in Clostridioides difficile
The bacterial enzymes FtsW and FtsI, encoded in the highly conserved dcw gene cluster,
are considered to be universally essential for the synthesis of septal peptidoglycan (PG) …
are considered to be universally essential for the synthesis of septal peptidoglycan (PG) …
Bacterial divisome protein FtsA forms curved antiparallel double filaments when binding to FtsN
T Nierhaus, SH McLaughlin, F Bürmann… - Nature …, 2022 - nature.com
During bacterial cell division, filaments of tubulin-like FtsZ form the Z-ring, which is the
cytoplasmic scaffold for divisome assembly. In Escherichia coli, the actin homologue FtsA …
cytoplasmic scaffold for divisome assembly. In Escherichia coli, the actin homologue FtsA …