Efficient codes and balanced networks

S Denève, CK Machens - Nature neuroscience, 2016 - nature.com
Recent years have seen a growing interest in inhibitory interneurons and their circuits. A
striking property of cortical inhibition is how tightly it balances excitation. Inhibitory currents …

Cortical connectivity and sensory coding

KD Harris, TD Mrsic-Flogel - Nature, 2013 - nature.com
The sensory cortex contains a wide array of neuronal types, which are connected together
into complex but partially stereotyped circuits. Sensory stimuli trigger cascades of electrical …

[HTML][HTML] A transcriptomic axis predicts state modulation of cortical interneurons

S Bugeon, J Duffield, M Dipoppa, A Ritoux, I Prankerd… - Nature, 2022 - nature.com
Transcriptomics has revealed that cortical inhibitory neurons exhibit a great diversity of fine
molecular subtypes,,,,–, but it is not known whether these subtypes have correspondingly …

[HTML][HTML] Systematic integration of structural and functional data into multi-scale models of mouse primary visual cortex

YN Billeh, B Cai, SL Gratiy, K Dai, R Iyer, NW Gouwens… - Neuron, 2020 - cell.com
Structural rules underlying functional properties of cortical circuits are poorly understood. To
explore these rules systematically, we integrated information from extensive literature …

[HTML][HTML] How inhibition shapes cortical activity

JS Isaacson, M Scanziani - Neuron, 2011 - cell.com
Cortical processing reflects the interplay of synaptic excitation and synaptic inhibition.
Rapidly accumulating evidence is highlighting the crucial role of inhibition in shaping …

Video-rate volumetric functional imaging of the brain at synaptic resolution

R Lu, W Sun, Y Liang, A Kerlin, J Bierfeld… - Nature …, 2017 - nature.com
Neurons and neural networks often extend hundreds of micrometers in three dimensions.
Capturing the calcium transients associated with their activity requires volume imaging …

Impact of perineuronal nets on electrophysiology of parvalbumin interneurons, principal neurons, and brain oscillations: a review

JC Wingert, BA Sorg - Frontiers in synaptic neuroscience, 2021 - frontiersin.org
Perineuronal nets (PNNs) are specialized extracellular matrix structures that surround
specific neurons in the brain and spinal cord, appear during critical periods of development …

Cross-modality sharpening of visual cortical processing through layer-1-mediated inhibition and disinhibition

LA Ibrahim, L Mesik, X Ji, Q Fang, H Li, Y Li, B Zingg… - Neuron, 2016 - cell.com
Cross-modality interaction in sensory perception is advantageous for animals' survival. How
cortical sensory processing is cross-modally modulated and what are the underlying neural …

Broadly tuned response properties of diverse inhibitory neuron subtypes in mouse visual cortex

AM Kerlin, ML Andermann, VK Berezovskii, RC Reid - Neuron, 2010 - cell.com
Different subtypes of GABAergic neurons in sensory cortex exhibit diverse morphology,
histochemical markers, and patterns of connectivity. These subtypes likely play distinct roles …

[HTML][HTML] Firing rate homeostasis in visual cortex of freely behaving rodents

KB Hengen, ME Lambo, SD Van Hooser, DB Katz… - Neuron, 2013 - cell.com
It has been postulated that homeostatic mechanisms maintain stable circuit function by
keeping neuronal firing within a set point range, but such firing rate homeostasis has never …