Efficient codes and balanced networks
S Denève, CK Machens - Nature neuroscience, 2016 - nature.com
Recent years have seen a growing interest in inhibitory interneurons and their circuits. A
striking property of cortical inhibition is how tightly it balances excitation. Inhibitory currents …
striking property of cortical inhibition is how tightly it balances excitation. Inhibitory currents …
Cortical connectivity and sensory coding
KD Harris, TD Mrsic-Flogel - Nature, 2013 - nature.com
The sensory cortex contains a wide array of neuronal types, which are connected together
into complex but partially stereotyped circuits. Sensory stimuli trigger cascades of electrical …
into complex but partially stereotyped circuits. Sensory stimuli trigger cascades of electrical …
[HTML][HTML] A transcriptomic axis predicts state modulation of cortical interneurons
Transcriptomics has revealed that cortical inhibitory neurons exhibit a great diversity of fine
molecular subtypes,,,,–, but it is not known whether these subtypes have correspondingly …
molecular subtypes,,,,–, but it is not known whether these subtypes have correspondingly …
[HTML][HTML] Systematic integration of structural and functional data into multi-scale models of mouse primary visual cortex
Structural rules underlying functional properties of cortical circuits are poorly understood. To
explore these rules systematically, we integrated information from extensive literature …
explore these rules systematically, we integrated information from extensive literature …
[HTML][HTML] How inhibition shapes cortical activity
JS Isaacson, M Scanziani - Neuron, 2011 - cell.com
Cortical processing reflects the interplay of synaptic excitation and synaptic inhibition.
Rapidly accumulating evidence is highlighting the crucial role of inhibition in shaping …
Rapidly accumulating evidence is highlighting the crucial role of inhibition in shaping …
Video-rate volumetric functional imaging of the brain at synaptic resolution
Neurons and neural networks often extend hundreds of micrometers in three dimensions.
Capturing the calcium transients associated with their activity requires volume imaging …
Capturing the calcium transients associated with their activity requires volume imaging …
Impact of perineuronal nets on electrophysiology of parvalbumin interneurons, principal neurons, and brain oscillations: a review
JC Wingert, BA Sorg - Frontiers in synaptic neuroscience, 2021 - frontiersin.org
Perineuronal nets (PNNs) are specialized extracellular matrix structures that surround
specific neurons in the brain and spinal cord, appear during critical periods of development …
specific neurons in the brain and spinal cord, appear during critical periods of development …
Cross-modality sharpening of visual cortical processing through layer-1-mediated inhibition and disinhibition
Cross-modality interaction in sensory perception is advantageous for animals' survival. How
cortical sensory processing is cross-modally modulated and what are the underlying neural …
cortical sensory processing is cross-modally modulated and what are the underlying neural …
Broadly tuned response properties of diverse inhibitory neuron subtypes in mouse visual cortex
AM Kerlin, ML Andermann, VK Berezovskii, RC Reid - Neuron, 2010 - cell.com
Different subtypes of GABAergic neurons in sensory cortex exhibit diverse morphology,
histochemical markers, and patterns of connectivity. These subtypes likely play distinct roles …
histochemical markers, and patterns of connectivity. These subtypes likely play distinct roles …
[HTML][HTML] Firing rate homeostasis in visual cortex of freely behaving rodents
It has been postulated that homeostatic mechanisms maintain stable circuit function by
keeping neuronal firing within a set point range, but such firing rate homeostasis has never …
keeping neuronal firing within a set point range, but such firing rate homeostasis has never …