Identified genetic variants from genome wide association studies frequently show only
modest effects on the disease risk, leading to the “missing heritability” problem. An avenue …

Background Genetic and epigenetic alterations have been indicated to be closely correlated
with the carcinogenesis, DNA methylation is one of most frequently occurring molecular …

Although genome-wide association studies (GWAS) have successfully identified thousands
of single nucleotide polymorphisms (SNPs) associated with common diseases, these …

Background and aim: In this study, we focused on the relationship between single
nucleotide polymorphisms in MMR genes and the occurrence and development of HBV …

机器学习方法在基因交互作用探测中的研究进展 Page 1 Hereditas (Beijing) 2018 年3 月, 40(3):
218―226 www.chinagene.cn 收稿日期: 2017-09-20; 修回日期: 2017-12-28 基金项目: 国家自然 …

Epithelial-mesenchymal transition (EMT) plays an important role in the development of
hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). We hypothesized that …

Knowledge discovery in database (KDD) is a process which is applied to possibly large
volumes of data for discovering patterns which can be significant and useful. In this thesis …

Pitting morphologies of E690 low-alloy steel in industrial and non-industrial marine splash
zones are statistically analyzed, including the influence of plastic deformation. Results show …

Genome-wide association studies (GWAS) is an effective way to reveal the pathogenic
genes of complex diseases by analyzing the genotype information and related disease …

In the beginning, I would like to thank my supervisor Amedeo Napoli for considering me
capable enough of doing a thesis, and my first co-supervisor Chedy Raïssi, who was …