Macrocyclization strategies for cyclic peptides and peptidomimetics
C Bechtler, C Lamers - RSC Medicinal Chemistry, 2021 - pubs.rsc.org
Peptides are a growing therapeutic class due to their unique spatial characteristics that can
target traditionally “undruggable” protein–protein interactions and surfaces. Despite their …
target traditionally “undruggable” protein–protein interactions and surfaces. Despite their …
Main methods and tools for peptide development based on protein-protein interactions (PPIs)
J Baeza, P Cruz, P Ojeda, F Adasme-Carreño… - 2024 - chemrxiv.org
Protein-protein interactions (PPIs) regulate crucial physiological and pathological
processes. PPIs are considered a class of biological targets almost infeasible for small …
processes. PPIs are considered a class of biological targets almost infeasible for small …