Biosystem‐inspired engineering of nanozymes for biomedical applications

L Zhang, H Wang, X Qu - Advanced Materials, 2024 - Wiley Online Library
Nanozymes with intrinsic enzyme‐mimicking activities have shown great potential to
become surrogates of natural enzymes in many fields by virtue of their advantages of high …

Supramolecular cancer nanotheranostics

J Zhou, L Rao, G Yu, TR Cook, X Chen… - Chemical Society …, 2021 - pubs.rsc.org
Among the many challenges in medicine, the treatment and cure of cancer remains an
outstanding goal given the complexity and diversity of the disease. Nanotheranostics, the …

Nanozyme: new horizons for responsive biomedical applications

D Jiang, D Ni, ZT Rosenkrans, P Huang… - Chemical Society …, 2019 - pubs.rsc.org
Nanozymes are nanomaterial-based artificial enzymes. By effectively mimicking catalytic
sites of natural enzymes or harboring multivalent elements for reactions, nanozyme systems …

Nanozymes: classification, catalytic mechanisms, activity regulation, and applications

Y Huang, J Ren, X Qu - Chemical reviews, 2019 - ACS Publications
Because of the high catalytic activities and substrate specificity, natural enzymes have been
widely used in industrial, medical, and biological fields, etc. Although promising, they often …

Bioorthogonal-activated in situ vaccine mediated by a COF-based catalytic platform for potent cancer immunotherapy

M Sun, Z Liu, L Wu, J Yang, J Ren… - Journal of the American …, 2023 - ACS Publications
Personalized tumor vaccines have become a promising modality for cancer immunotherapy.
However, in situ personalized tumor vaccines generated from immunogenic cancer cell …

Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes (II)

J Wu, X Wang, Q Wang, Z Lou, S Li, Y Zhu… - Chemical Society …, 2019 - pubs.rsc.org
Nanozymes are nanomaterials with enzyme-like characteristics (Chem. Soc. Rev., 2013, 42,
6060–6093). They have been developed to address the limitations of natural enzymes and …

Integrated cascade nanozyme catalyzes in vivo ROS scavenging for anti-inflammatory therapy

Y Liu, Y Cheng, H Zhang, M Zhou, Y Yu, S Lin… - Science …, 2020 - science.org
Here, an integrated cascade nanozyme with a formulation of Pt@ PCN222-Mn is developed
to eliminate excessive reactive oxygen species (ROS). This nanozyme mimics superoxide …

Designing nanozymes for in vivo applications

R Zhang, B Jiang, K Fan, L Gao, X Yan - Nature Reviews …, 2024 - nature.com
Biocatalytic drugs, including natural and artificial enzymes that can accelerate biochemical
reactions, are promising tools to address redox imbalances, metabolic disorders and …

Bioorthogonal catalytic patch

Z Chen, H Li, Y Bian, Z Wang, G Chen, X Zhang… - Nature …, 2021 - nature.com
Bioorthogonal catalysis mediated by transition metals has inspired a new subfield of artificial
chemistry complementary to enzymatic reactions, enabling the selective labelling of …

An Orally Administered CeO2@Montmorillonite Nanozyme Targets Inflammation for Inflammatory Bowel Disease Therapy

S Zhao, Y Li, Q Liu, S Li, Y Cheng… - Advanced Functional …, 2020 - Wiley Online Library
Safe, effective, and convenient administration of therapeutic nanomaterials is one of the
greatest difficulties in nanomedicine. To tackle this challenge, a system which couples multi …