Natural polymers, because of their biocompatibility, availability, and physico-chemical
properties have been the materials of choice for the fabrication of injectable hydrogels for …

Study Design. Cell viability was assessed in relation to cell clustering, and mechanisms of
cell–cell signaling in the clusters were investigated. Objectives. To explore the functional …

Objective To perform a large‐scale association analysis of single‐nucleotide polymorphisms
(SNPs) in patients with radiographically defined osteoarthritis (OA) of the knee. Methods We …

Heparin has been widely investigated in medicine and biomedical applications as an
anticoagulant. This paper described a covalent modification of poly (lactic acid)(PLA) films …

Objective: As a main cellular component within the disc, nucleus pulposus (NP) cells play
important roles in disc physiology. However, little is known on the biologic hallmarks of …

Intervertebral disc (IVD) degeneration is strongly associated with low back pain, a major
cause of disability worldwide. An in‐depth understanding of IVD cell physiology is required …

Study Design. We evaluated the influence of rabbit notochordal cells on the expression of
inflammatory mediators by human annulus fibrosus (AF) cells cocultured with macrophage …

Objective Notochordal cells in the intervertebral disc interact with nucleus pulposus (NP)
cells and support the maintenance of disc homeostasis by regulation of matrix production …

目的综述椎间盘组织工程支架材料及其应用的研究现状. 方法广泛查阅近年来有关椎间盘组织
工程支架材料及其应用的文献, 进行综述. 结果琼脂糖凝胶, 藻酸盐凝胶, Ⅰ …

This study was conducted to determine physiological and functional features of primary and
immortalized canine chondrocytes. Chondrocytes were immortalized by introducing the …