Ventilator-associated pneumonia

J Chastre, JY Fagon - American journal of respiratory and critical …, 2002 - atsjournals.org
Ventilator-associated pneumonia (VAP) continues to complicate the course of 8 to 28% of
patients receiving mechanical ventilation (MV). In contrast to infections of more frequently …

Ventilator-associated pneumonia: diagnosis, treatment, and prevention

SM Koenig, JD Truwit - Clinical microbiology reviews, 2006 - Am Soc Microbiol
While critically ill patients experience a life-threatening illness, they commonly contract
ventilator-associated pneumonia. This nosocomial infection increases morbidity and likely …

Ventilator-associated pneumonia in critically ill patients with COVID-19

M Maes, E Higginson, J Pereira-Dias, MD Curran… - Critical Care, 2021 - Springer
Background Pandemic COVID-19 caused by the coronavirus SARS-CoV-2 has a high
incidence of patients with severe acute respiratory syndrome (SARS). Many of these patients …

Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia

American Thoracic Society… - American journal of …, 2005 - search.proquest.com
EXECUTIVE SUMMARY Since the initial 1996 American Thoracic Society (ATS) guideline
on nosocomial pneumonia, a number of new developments have appeared, mandating a …

Persistent elevation of inflammatory cytokines predicts a poor outcome in ARDS: plasma IL-1β and IL-6 levels are consistent and efficient predictors of outcome over …

GU Meduri, S Headley, G Kohler, F Stentz, E Tolley… - Chest, 1995 - Elsevier
Background Inflammatory cytokines have been related to the development of adult
respiratory distress syndrome (ARDS), shock, and multiple organ dysfunction syndrome …

A comparison of noninvasive positive-pressure ventilation and conventional mechanical ventilation in patients with acute respiratory failure

M Antonelli, G Conti, M Rocco, M Bufi… - … England Journal of …, 1998 - Mass Medical Soc
Background and Methods The role of noninvasive positive-pressure ventilation delivered
through a face mask in patients with acute respiratory failure is uncertain. We conducted a …

Methylprednisolone infusion in early severe ARDS: results of a randomized controlled trial

GU Meduri, E Golden, AX Freire, E Taylor, M Zaman… - Chest, 2007 - Elsevier
Objective To determine the effects of low-dose prolonged methylprednisolone infusion on
lung function in patients with early severe ARDS. Design Randomized, double-blind …

Effect of prolonged methylprednisolone therapy in unresolving acute respiratory distress syndrome: a randomized controlled trial

GU Meduri, AS Headley, E Golden, SJ Carson… - Jama, 1998 - jamanetwork.com
Context.—No pharmacological therapeutic protocol has been found effective in modifying
the clinical course of acute respiratory distress syndrome (ARDS) and mortality remains …

Short-course empiric antibiotic therapy for patients with pulmonary infiltrates in the intensive care unit: a proposed solution for indiscriminate antibiotic prescription

N Singh, P Rogers, CW Atwood… - American journal of …, 2000 - atsjournals.org
Inappropriate antibiotic use for pulmonary infiltrates is common in the intensive care unit
(ICU). We sought to devise an approach that would minimize unnecessary antibiotic use …

Inflammatory cytokines in the BAL of patients with ARDS: persistent elevation over time predicts poor outcome

GU Meduri, G Kohler, S Headley, E Tolley, F Stentz… - Chest, 1995 - Elsevier
Background Inflammatory cytokines (ICs) are important modulators of injury and repair. ICs
have been found to be elevated in the BAL of patients with both early and late ARDS. We …