[HTML][HTML] The Use of Artificial Intelligence to Analyze the Exposome in the Development of Chronic Diseases: A Review of the Current Literature

S Isola, G Murdaca, S Brunetto, E Zumbo, A Tonacci… - Informatics, 2024 - mdpi.com
The “Exposome” is a concept that indicates the set of exposures to which a human is
subjected during their lifetime. These factors influence the health state of individuals and can …

Understanding exposomes and its relation with cancer risk in Malaysia based on epidemiological evidence: a narrative review

R Sharif, TC Ooi - Genes and Environment, 2024 - Springer
The prevalence of cancer is increasing globally, and Malaysia is no exception. The
exposome represents a paradigm shift in cancer research, emphasizing the importance of a …

Race/ethnicity-stratified fine-mapping of the MHC locus reveals genetic variants associated with late-onset asthma

EY Lee, W Choi, AB Burkholder, L Perera… - Frontiers in …, 2023 - frontiersin.org
Introduction: Asthma is a chronic disease of the airways that impairs normal breathing. The
etiology of asthma is complex and involves multiple factors, including the environment and …

Combined Exposures and Mixtures Research: An Enduring NIEHS Priority

DJ Carlin, CV Rider - Environmental Health Perspectives, 2024 - ehp.niehs.nih.gov
Background: The National Institute of Environmental Health Sciences (NIEHS) continues to
prioritize research to better understand the health effects resulting from exposure to mixtures …

An atlas on multitudinous risk factors associated with incident hypertension: comprehensive exposome-wide association and wide-angled genetic analyses

H Yang, Y Jiang, J Guo, J Wang, X Ma… - European Journal of …, 2024 - academic.oup.com
Aims Despite numerous risk factors being associated with hypertension, the breadth of
research remains constrained, with a notable absence of systematic, data-driven exploration …

Towards Personalized Cardiometabolic Risk Prediction: A Fusion of Exposome and AI

Z Shahbazi, S Nowaczyk - Heliyon, 2024 - cell.com
The influence of the exposome on major health conditions like cardiovascular disease
(CVD) is widely recognized. However, integrating diverse exposome factors into predictive …

Questionnaire-based exposome-wide association studies for common diseases in the Personalized Environment and Genes Study

D Lloyd, JS House, FS Akhtari, CP Schmitt… - …, 2024 - academic.oup.com
The exposome collectively refers to all exposures, beginning in utero and continuing
throughout life, and comprises not only standard environmental exposures such as point …

Interactive data sharing for multiple questionnaire-based exposome-wide association studies and exposome correlations in the Personalized Environment and Genes …

D Lloyd, JS House, FS Akhtari, CP Schmitt… - …, 2024 - academic.oup.com
The correlations among individual exposures in the exposome, which refers to all exposures
an individual encounters throughout life, are important for understanding the landscape of …

Exposomics and Cardiovascular Diseases: A Scoping Review of Machine Learning Approaches

KD Argyri, IK Gallos, A Amditis, DD Dionysiou - medRxiv, 2024 - medrxiv.org
Cardiovascular disease has been established as the world's number one killer, causing over
20 million deaths per year. This fact, along with the growing awareness of the impact of …

Questionnaire-based polyexposure assessment outperforms polygenic scores for classification of type 2 diabetes in a multiancestry cohort

FS Akhtari, D Lloyd, A Burkholder, X Tong… - Diabetes …, 2023 - Am Diabetes Assoc
OBJECTIVE Environmental exposures may have greater predictive power for type 2
diabetes than polygenic scores (PGS). Studies examining environmental risk factors …