C2H2-type zinc finger proteins: evolutionarily old and new partners of the nuclear hormone receptors
R Mackeh, AK Marr, A Fadda… - Nuclear receptor …, 2018 - journals.sagepub.com
Nuclear hormone receptors (NRs) are evolutionarily conserved ligand-dependent
transcription factors. They are essential for human life, mediating the actions of lipophilic …
transcription factors. They are essential for human life, mediating the actions of lipophilic …
[HTML][HTML] Glucocorticoid receptor
The glucocorticoid receptor (GR) is an evolutionally conserved nuclear receptor superfamily
protein that mediates the diverse actions of glucocorticoids as a ligand-dependent …
protein that mediates the diverse actions of glucocorticoids as a ligand-dependent …
Genome-Wide Identification of C2H2 ZFPs and Functional Analysis of BRZAT12 under Low-Temperature Stress in Winter Rapeseed (Brassica rapa)
L Ma, J Xu, X Tao, J Wu, W Wang, Y Pu… - International Journal of …, 2022 - mdpi.com
Zinc-finger protein (ZFP) transcription factors are among the largest families of transcription
factors in plants. They participate in various biological processes such as apoptosis …
factors in plants. They participate in various biological processes such as apoptosis …
[HTML][HTML] CTCF as an example of DNA-binding transcription factors containing clusters of C2H2-type zinc fingers
OG Maksimenko, DV Fursenko, EV Belova… - Acta …, 2021 - ncbi.nlm.nih.gov
In mammals, most of the boundaries of topologically associating domains and all well-
studied insulators are rich in binding sites for the CTCF protein. According to existing …
studied insulators are rich in binding sites for the CTCF protein. According to existing …
SIRT1 is a transcriptional enhancer of the glucocorticoid receptor acting independently to its deacetylase activity
S Suzuki, JR Iben, SL Coon, T Kino - Molecular and cellular endocrinology, 2018 - Elsevier
Glucocorticoids have strong effects on diverse human activities through the glucocorticoid
receptor (GR). Sirtuin 1 (SIRT1) is a NAD+-dependent histone deacetylase and promotes …
receptor (GR). Sirtuin 1 (SIRT1) is a NAD+-dependent histone deacetylase and promotes …
[HTML][HTML] Zinc salicylate reduces airway smooth muscle cells remodelling by blocking mTOR and activating p21 (Waf1/Cip1)
L Fang, M Roth, CT S'ng, M Tamm, B Han… - The Journal of Nutritional …, 2021 - Elsevier
Asthma is characterized by chronic inflammation and tissue remodeling of the airways.
Remodeling is resistant to pharmaceutical therapies. This study investigated the effect of …
Remodeling is resistant to pharmaceutical therapies. This study investigated the effect of …
Prediction and assessment of deleterious and disease causing nonsynonymous single nucleotide polymorphisms (nsSNPs) in human FOXP4 gene: An in silico study
In humans, FOXP gene family is involved in embryonic development and cancer
progression. The FOXP4 (Forkhead box protein P4) gene belongs to this FOXP gene family …
progression. The FOXP4 (Forkhead box protein P4) gene belongs to this FOXP gene family …
Proteomic sift through serum and endometrium profiles unraveled signature proteins associated with subdued fertility and dampened endometrial receptivity in women …
N Rashid, A Nigam, SK Jain, SH Naqvi, S Wajid - Cell and tissue research, 2020 - Springer
The objective of this study is to discern the proteomic differences responsible for hampering
the receptivity of endometrium and subduing the fertility of females with polycystic ovary …
the receptivity of endometrium and subduing the fertility of females with polycystic ovary …
[HTML][HTML] Identification of key regulatory genes in the pathogenesis of COVID-19 and sepsis: An observational study
X Chen, F Yang, G Luo - Medicine, 2024 - journals.lww.com
Patients with severe COVID-19 and those with sepsis have similar clinical manifestations.
We used bioinformatics methods to identify the common hub genes in these 2 diseases. Two …
We used bioinformatics methods to identify the common hub genes in these 2 diseases. Two …
Tissue specific expression of sialic acid metabolic pathway: role in GNE myopathy
K Awasthi, A Srivastava, S Bhattacharya… - Journal of Muscle …, 2021 - Springer
GNE myopathy is an adult-onset degenerative muscle disease that leads to extreme
disability in patients. Biallelic mutations in the rate-limiting enzyme UDP-N …
disability in patients. Biallelic mutations in the rate-limiting enzyme UDP-N …