Abstract Drosophila suzukii (Matsumura)(Diptera: Drosophilidae) also known as spotted-
wing drosophila (SWD), is a pest native to Southeast Asia. In the last few decades, the pest …

Gene drives are selfish genetic elements that are transmitted to progeny at super-Mendelian
(> 50%) frequencies. Recently developed CRISPR–Cas9-based gene-drive systems are …

According to Darwin's theory, endless evolution leads to a revolution. One such example is
the Clustered Regularly Interspaced Palindromic Repeats (CRISPR)–Cas system, an …

Mosquito-borne diseases, such as dengue and malaria, pose significant global health
burdens. Unfortunately, current control methods based on insecticides and environmental …

The majority of conservation efforts and public attention are focused on large, charismatic
mammals and birds such as tigers, pandas and penguins, yet the bulk of animal life, whether …

Abstract Cas9/gRNA-mediated gene-drive systems have advanced development of genetic
technologies for controlling vector-borne pathogen transmission. These technologies …

Only female insects transmit diseases such as malaria, dengue and Zika; therefore, control
methods that bias the sex ratio of insect offspring have long been sought. Genetic elements …

CRISPR-based gene-drives targeting the gene doublesex in the malaria vector Anopheles
gambiae effectively suppressed the reproductive capability of mosquito populations reared …

Genome editing took a dramatic turn with the development of the clustered regularly
interspaced short palindromic repeats (CRISPR)-CRISPR-associated proteins (Cas) system …

Synthetic biology allows us to bioengineer cells to synthesize novel valuable molecules
such as renewable biofuels or anticancer drugs. However, traditional synthetic biology …