[HTML][HTML] Brain malignancies: Glioblastoma and brain metastases

TT Lah, M Novak, B Breznik - Seminars in cancer biology, 2020 - Elsevier
Brain, the major organ of the central nervous system controls and processes most of body
activities. Therefore, the most aggressive brain tumor–glioblastoma and metastases from …

[HTML][HTML] Quiescence of adult mammalian neural stem cells: a highly regulated rest

N Urbán, IM Blomfield, F Guillemot - Neuron, 2019 - cell.com
Neural stem cells in the adult mammalian brain are the source of new neurons that
contribute to complex sensory and cognitive functions. Most adult neural stem cells are …

Young CSF restores oligodendrogenesis and memory in aged mice via Fgf17

T Iram, F Kern, A Kaur, S Myneni, AR Morningstar… - Nature, 2022 - nature.com
Recent understanding of how the systemic environment shapes the brain throughout life has
led to numerous intervention strategies to slow brain ageing,–. Cerebrospinal fluid (CSF) …

[HTML][HTML] SARS-CoV-2 infects the brain choroid plexus and disrupts the blood-CSF barrier in human brain organoids

L Pellegrini, A Albecka, DL Mallery, MJ Kellner, D Paul… - Cell stem cell, 2020 - cell.com
Summary Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) virus, leads to respiratory symptoms that can be …

Cerebrospinal fluid regulates skull bone marrow niches via direct access through dural channels

JA Mazzitelli, LCD Smyth, KA Cross, T Dykstra… - Nature …, 2022 - nature.com
It remains unclear how immune cells from skull bone marrow niches are recruited to the
meninges. Here we report that cerebrospinal fluid (CSF) accesses skull bone marrow via …

[HTML][HTML] The meningeal lymphatic system: a new player in neurophysiology

S Da Mesquita, Z Fu, J Kipnis - Neuron, 2018 - cell.com
The nature of fluid dynamics within the brain parenchyma is a focus of intensive research. Of
particular relevance is its participation in diseases associated with protein accumulation and …

Neural stem cells: origin, heterogeneity and regulation in the adult mammalian brain

K Obernier, A Alvarez-Buylla - Development, 2019 - journals.biologists.com
In the adult rodent brain, neural stem cells (NSCs) persist in the ventricular-subventricular
zone (V-SVZ) and the subgranular zone (SGZ), which are specialized niches in which young …

[HTML][HTML] Adult mammalian neural stem cells and neurogenesis: five decades later

AM Bond, G Ming, H Song - Cell stem cell, 2015 - cell.com
Adult somatic stem cells in various organs maintain homeostatic tissue regeneration and
enhance plasticity. Since its initial discovery five decades ago, investigations of adult …

[HTML][HTML] Molecular identity of human outer radial glia during cortical development

AA Pollen, TJ Nowakowski, J Chen, H Retallack… - Cell, 2015 - cell.com
Radial glia, the neural stem cells of the neocortex, are located in two niches: the ventricular
zone and outer subventricular zone. Although outer subventricular zone radial glia may …

The adult ventricular–subventricular zone (V-SVZ) and olfactory bulb (OB) neurogenesis

DA Lim, A Alvarez-Buylla - Cold Spring Harbor …, 2016 - cshperspectives.cshlp.org
A large population of neural stem/precursor cells (NSCs) persists in the ventricular–
subventricular zone (V-SVZ) located in the walls of the lateral brain ventricles. V-SVZ NSCs …