Epidemiology and burden of human papillomavirus and related diseases, molecular pathogenesis, and vaccine evaluation

AJ Kombe Kombe, B Li, A Zahid, HM Mengist… - Frontiers in public …, 2021 - frontiersin.org
Diagnosed in more than 90% of cervical cancers, the fourth deadliest cancer in women,
human papillomavirus (HPV) is currently the most common pathogen responsible for female …

[HTML][HTML] Human papillomavirus vaccine against cervical cancer: Opportunity and challenge

R Wang, W Pan, L Jin, W Huang, Y Li, D Wu, C Gao… - Cancer letters, 2020 - Elsevier
Cervical cancer is one of the most common cancers threatening women's health, and the
persistent infection of high-risk human papillomavirus (HPV) is closely related to the …

Heparan sulfate proteoglycans and viral attachment: true receptors or adaptation bias?

V Cagno, ED Tseligka, ST Jones, C Tapparel - Viruses, 2019 - mdpi.com
Heparan sulfate proteoglycans (HSPG) are composed of unbranched, negatively charged
heparan sulfate (HS) polysaccharides attached to a variety of cell surface or extracellular …

Furin‐mediated protein processing in infectious diseases and cancer

E Braun, D Sauter - Clinical & translational immunology, 2019 - Wiley Online Library
Proteolytic cleavage regulates numerous processes in health and disease. One key player
is the ubiquitously expressed serine protease furin, which cleaves a plethora of proteins at …

The human papillomavirus replication cycle, and its links to cancer progression: a comprehensive review

SV Graham - Clinical science, 2017 - portlandpress.com
HPVs (human papillomaviruses) infect epithelial cells and their replication cycle is intimately
linked to epithelial differentiation. There are over 200 different HPV genotypes identified to …

HPV and cervical cancer: A review of epidemiology and screening uptake in the UK

S Choi, A Ismail, G Pappas-Gogos, S Boussios - Pathogens, 2023 - mdpi.com
Cervical cancer is the fourth most common malignancy in females worldwide, and a leading
cause of death in the United Kingdom (UK). The human papillomavirus (HPV) is the …

[HTML][HTML] Opportunities and challenges for human papillomavirus vaccination in cancer

R Roden, PL Stern - Nature Reviews Cancer, 2018 - nature.com
The discovery of genotype 16 as the prototype oncogenic human papillomavirus (HPV)
initiated a quarter century of laboratory and epidemiological studies that demonstrated their …

Host cell proteases: critical determinants of coronavirus tropism and pathogenesis

JK Millet, GR Whittaker - Virus research, 2015 - Elsevier
Coronaviruses are a large group of enveloped, single-stranded positive-sense RNA viruses
that infect a wide range of avian and mammalian species, including humans. The …

Host cell entry of Middle East respiratory syndrome coronavirus after two-step, furin-mediated activation of the spike protein

JK Millet, GR Whittaker - Proceedings of the National …, 2014 - National Acad Sciences
Middle East respiratory syndrome coronavirus (MERS-CoV) is a newly identified
betacoronavirus causing high morbidity and mortality in humans. The coronavirus spike (S) …

The biology and life-cycle of human papillomaviruses

J Doorbar, W Quint, L Banks, IG Bravo, M Stoler… - Vaccine, 2012 - Elsevier
Human papillomaviruses (HPVs) comprise a diverse group, and have different epithelial
tropisms and life-cycle strategies. Many HPVs are classified as low-risk, as they are only …