[HTML][HTML] Fibroblast activation protein-based theranostics in cancer research: a state-of-the-art review
In recent years, quinoline-based fibroblast activation protein (FAP) inhibitors (FAPI) have
shown promising results in the diagnosis of cancer and several other diseases, making them …
shown promising results in the diagnosis of cancer and several other diseases, making them …
[HTML][HTML] FAP and FAPI-PET/CT in malignant and non-malignant diseases: a perfect symbiosis?
K Dendl, SA Koerber, C Kratochwil, J Cardinale… - Cancers, 2021 - mdpi.com
Simple Summary FAPI represents a novel class of radiotracers demonstrating promising
results in terms of a high uptake in concordance with low background noise in several …
results in terms of a high uptake in concordance with low background noise in several …
[HTML][HTML] Head-to-Head Comparison of Fibroblast Activation Protein Inhibitors (FAPI) Radiotracers versus [18F]F-FDG in Oncology: A Systematic Review
G Treglia, B Muoio, H Roustaei, Z Kiamanesh… - International Journal of …, 2021 - mdpi.com
Several recent studies comparing radiolabeled fibroblast activation protein inhibitors (FAPI)
and fluorine-18 fluorodeoxyglucose ([18F] F-FDG) as positron emission tomography (PET) …
and fluorine-18 fluorodeoxyglucose ([18F] F-FDG) as positron emission tomography (PET) …
[HTML][HTML] Fibroblast-activated protein inhibitor PET/CT: cancer diagnosis and management
S Kuyumcu, Y Sanli, RM Subramaniam - Frontiers in oncology, 2021 - frontiersin.org
Fibroblast activation protein (FAP), overexpressed on cancer-associated fibroblasts (CAF), is
a novel target for molecular imaging of various tumors. Recently, the development of several …
a novel target for molecular imaging of various tumors. Recently, the development of several …
Accurate preoperative staging with [68Ga]Ga-FAPI PET/CT for patients with oral squamous cell carcinoma: a comparison to 2-[18F]FDG PET/CT
S Chen, Z Chen, G Zou, S Zheng, K Zheng, J Zhang… - European …, 2022 - Springer
Objective To evaluate the potential value of [68Ga] Ga-labelled fibroblast activation protein
inhibitor ([68Ga] Ga-FAPI) positron emission tomography/computed tomography (PET/CT) in …
inhibitor ([68Ga] Ga-FAPI) positron emission tomography/computed tomography (PET/CT) in …
Could Fibroblast Activation Protein (FAP)‐Specific Radioligands Be Considered as Pan‐Tumor Agents?
H Roustaei, Z Kiamanesh, E Askari… - Contrast Media & …, 2022 - Wiley Online Library
Background. Cancer‐associated fibroblasts (CAFs) can strongly modulate the response to
therapy of malignant tumor cells, facilitating their continuous proliferation and invading …
therapy of malignant tumor cells, facilitating their continuous proliferation and invading …
[HTML][HTML] Head-to-head comparison of FDG and radiolabeled FAPI PET: a systematic review of the literature
FAPI-based radiopharmaceuticals are a novel class of tracers, mainly used for PET imaging,
which have demonstrated several advantages over [18F] FDG, especially in the case of low …
which have demonstrated several advantages over [18F] FDG, especially in the case of low …
The performance of 68Ga-FAPI-04 PET/CT in head and neck squamous cell carcinoma: a prospective comparison with 18F-FDG PET/CT
Y Jiang, B Wen, C Li, Y Tian, Z Xiao, K Xu… - European Journal of …, 2023 - Springer
Purpose This study was designed to compare the performance of 68Ga-FAPI-04 and 18F-
FDG PET/CT for initial staging and recurrence detection of head and neck squamous cell …
FDG PET/CT for initial staging and recurrence detection of head and neck squamous cell …
[HTML][HTML] Associations between normal organs and tumor burden in patients imaged with fibroblast activation protein inhibitor-directed positron emission tomography
A Kosmala, SE Serfling, N Dreher, T Lindner… - Cancers, 2022 - mdpi.com
Simple Summary Several radiolabeled fibroblast activation protein targeted inhibitors (FAPI)
have been developed for molecular imaging and therapy. A potential correlation of …
have been developed for molecular imaging and therapy. A potential correlation of …
Evaluation of the diagnostic accuracy of FAPI PET/CT in oncologic studies: systematic review and metaanalysis
G Wass, K Clifford… - Journal of Nuclear …, 2023 - Soc Nuclear Med
Fibroblast-activation protein is a promising target for oncologic molecular imaging. Studies
show that fibroblast activation protein inhibitor (FAPI) radiotracers are accurate diagnostics …
show that fibroblast activation protein inhibitor (FAPI) radiotracers are accurate diagnostics …