Heart transplantation (HTx) surgically interrupts the parasympathetic vagal neurons and the
intrinsic postganglionic sympathetic nerve fibers traveling from the stellate ganglia to the …

Innervation plays a pivotal role as a driver of tissue and organ development as well as a
means for their functional control and modulation. Therefore, innervation should be carefully …

Rett syndrome (RTT), mainly caused by mutations in methyl-CpG binding protein 2
(MeCP2), is one of the most prevalent intellectual disorders without effective therapies. Here …

Heart transplantation results in complete denervation of the donor heart with loss of afferent
and efferent nerve connections. The majority of patients remain completely denervated …

While life expectancy is greatly improved after a heart transplant, survival is still limited, and
compared to the general population, the exercise capacity and health-related quality of life …

Cardiac neuroimaging with 123 I-metaiodobenzylguanidine (123 I-MIBG) has been officially
used in clinical practice in Japan since 1992. The nuclear cardiology guidelines of the …

Objectives: Muscle wasting and exercise intolerance are common in heart transplant
recipients. Most studies on the effects of exercise training have used relatively small sample …

Nuclear cardiology has made significant advances since the first reports of planar
scintigraphy for the evaluation of left ventricular perfusion and function. While the current …

BACKGROUND: Cross-sectional studies suggest, by use of heart rate variability (HRV), that
partial re-innervation of the sinus node may occur after heart transplantation (HTx). Our aim …

Objective: Partial normalization of the heart rate (HR) response can take place some time
after heart transplantation (HTx), but the extent to which this occurs, its time course, and …