Cryo-electron tomography (CET) utilizes a combination of specimen cryo-fixation and multi-
angle electron microscopy imaging to produce three-dimensional (3D) volume …

The term “intracellular complement” has been introduced recently as an umbrella term to
distinguish functions of complement proteins that take place intracellularly, rather than in the …

IgG3 is unique among the IgG subclasses due to its extended hinge, allotypic diversity and
enhanced effector functions, including highly efficient pathogen neutralisation and …

Antigen binding by serum Ig-M (IgM) protects against microbial infections and helps to
prevent autoimmunity, but causes life-threatening diseases when mistargeted. How antigen …

Danger patterns on microbes or damaged host cells bind and activate C1, inducing innate
immune responses and clearance through the complement cascade. How these patterns …

In recent data, Optical character recognition (OCR) systems have laid hands in the field of
most popular language recognitions. Unlike other languages, the Tamil language is more …

Properdin (FP) is a positive regulator of the immune system stimulating the activity of the
proteolytically active C3 convertase C3bBb in the alternative pathway of the complement …

The human immune system can directly lyse invading micro‐organisms and aberrant host
cells by generating pores in the cell envelope, called membrane attack complexes (MACs) …

Structures of alternative pathway proteins have offered a comprehensive structural basis for
understanding the molecular mechanisms governing activation and regulation of the …

Single particle tomography (SPT), also known as subtomogram averaging, is a powerful
technique uniquely poised to address questions in structural biology that are not amenable …